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TDT Protein, Human, Recombinant (His)

TDT Protein, Human, Recombinant (His)

产品编号 TMPJ-00765
别名: Terminal transferase, Terminal deoxynucleotidyltr, DNTT, Terminal deoxynucleotidyltransferase, DNA nucleotidylexotransferase, TDT, Terminal addition enzyme

Terminal deoxynucleotidyl transferase (TdT) is a highly conserved vertebrate enzyme that possesses the unique ability to catalyze the random addition of deoxynucleoside 5'-triphosphates onto the 3'-hydroxyl group of a single-stranded DNA. It plays an important role in the generation of immunoglobin and T-cell receptor diversity. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.

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TDT Protein, Human, Recombinant (His)
规格 价格/CNY 货期 数量
10 μg ¥ 980 5日内发货
50 μg ¥ 2,960 5日内发货
500 μg ¥ 14,800 5日内发货
1 mg ¥ 22,200 5日内发货
药物设计专题培训
千万补贴 助力科研
BCA蛋白浓度测定试剂盒限时半价
产品目录号及名称: TDT Protein, Human, Recombinant (His) (TMPJ-00765)
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产品性质
产品描述 Terminal deoxynucleotidyl transferase (TdT) is a highly conserved vertebrate enzyme that possesses the unique ability to catalyze the random addition of deoxynucleoside 5'-triphosphates onto the 3'-hydroxyl group of a single-stranded DNA. It plays an important role in the generation of immunoglobin and T-cell receptor diversity. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.
种属 Human
表达系统 E. coli
标签 N-6xHis
蛋白编号 P04053
别名 Terminal transferase, Terminal deoxynucleotidyltr, DNTT, Terminal deoxynucleotidyltransferase, DNA nucleotidylexotransferase, TDT, Terminal addition enzyme
氨基酸序列 Met1-Ala509
蛋白构建 Met1-Ala509
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 62 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Supplied as a 0.2 μm filtered solution of 0.1M KH<sub>2</sub>PO<sub>4</sub>, 200 mM KCl, 1 mM 2-Mercaptoethanol, 50% Glycerol, pH 7.2.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Terminal deoxynucleotidyl transferase (TdT) is a highly conserved vertebrate enzyme that possesses the unique ability to catalyze the random addition of deoxynucleoside 5'-triphosphates onto the 3'-hydroxyl group of a single-stranded DNA. It plays an important role in the generation of immunoglobin and T-cell receptor diversity. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells.

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Keywords

TDT Protein, Human, Recombinant (His) Terminal transferase Terminal deoxynucleotidyltr DNTT Terminal deoxynucleotidyltransferase DNA nucleotidylexotransferase TDT Terminal addition enzyme recombinant recombinant-proteins proteins protein

 

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