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Anti-IL-32 alpha/IL32A Antibody (2S286)

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产品编号 TMAY-01582

Anti-IL-32 alpha/IL32A Antibody (2S286) 是一种 Mouse 抗体,靶向 IL-32 alpha/IL32A。Anti-IL-32 alpha/IL32A Antibody (2S286) 可用于 WB。

Anti-IL-32 alpha/IL32A Antibody (2S286)

Anti-IL-32 alpha/IL32A Antibody (2S286)

Rating icon 还可以
产品编号 TMAY-01582

Anti-IL-32 alpha/IL32A Antibody (2S286) 是一种 Mouse 抗体,靶向 IL-32 alpha/IL32A。Anti-IL-32 alpha/IL32A Antibody (2S286) 可用于 WB。

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产品介绍

生物活性
产品描述
Anti-IL-32 alpha/IL32A Antibody (2S286) is a Mouse antibody targeting IL-32 alpha/IL32A. Anti-IL-32 alpha/IL32A Antibody (2S286) can be used in WB.
Ig Type
Monoclonal Mouse IgG2a
克隆号
2S286
交叉反应
Human
验证活性
Anti-IL32A mouse monoclonal antibody at 1:500 dilution.

-Lane A: Jurkat Whole Cell lysate.

-Lysates/proteins at 30 μg per lane.

-Secondary

-Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution.

-Developed using the Odyssey technique.

-Performed under reducing conditions.

-Predicted band size:26 kDa.

-Observed band size:30 kDa(We are unsure as to the identity of these extra bands.)
应用
WB
推荐剂量
WB: 1:500-1:1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL-32 alpha / IL32A (rh IL-32 alpha / IL32A; TMPY-01033; NP_001012651.1; Met1-Lys131). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathways. It is regulated robustly by other major proinflammatory cytokines and is crucial to inflammation and immune responses. Four of the IL-32 isoforms (alpha, beta, gamma, and delta) are the most representative IL-32 transcripts, and the gamma isoform of IL-32 is the most active, although all isoforms are biologically active. IL-32, a cytokine produced mainly by T, natural killer, and epithelial cells induces significant amounts of TNFalpha and MIP-2 and increases the production of both cytokines in a dose-dependent manner. IL-32 has been implicated in inflammatory disorders, Mycobacterium tuberculosis infections, inflammatory bowel disease, and influenza A virus infection, as well as in some autoimmune diseases, such as rheumatoid arthritis, ulcerative colitis, and in the human stomach cancer, human lung cancer, and breast cancer tissues. Thus, IL-32 expression might be valuable as a biomarker for cancer.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human IL-32 alpha / IL32A Protein (TMPY-01033)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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