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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-PLCZ1 Polyclonal Antibody

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货号 TMAB-01549

别名 Testis-development protein NYD-SP27, PLCZ1, Phospholipase C-zeta-1 (PLC-zeta-1), Phosphoinositide phospholipase C-zeta-1, 5-bisphosphate phosphodiesterase zeta-1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1

Anti-PLCZ1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PLCZ1。Anti-PLCZ1 Polyclonal Antibody 可用于 IF,IHC-Fr。

Anti-PLCZ1 Polyclonal Antibody

Anti-PLCZ1 Polyclonal Antibody

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货号 TMAB-01549 别名 Testis-development protein NYD-SP27, PLCZ1, Phospholipase C-zeta-1 (PLC-zeta-1), Phosphoinositide phospholipase C-zeta-1, 5-bisphosphate phosphodiesterase zeta-1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1

Anti-PLCZ1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 PLCZ1。Anti-PLCZ1 Polyclonal Antibody 可用于 IF,IHC-Fr。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-PLCZ1 Polyclonal Antibody is a Rabbit antibody targeting PLCZ1. Anti-PLCZ1 Polyclonal Antibody can be used in IF,IHC-Fr.
别名Testis-development protein NYD-SP27, PLCZ1, Phospholipase C-zeta-1 (PLC-zeta-1), Phosphoinositide phospholipase C-zeta-1, 5-bisphosphate phosphodiesterase zeta-1, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Dog,Pig,Cow,Horse)
验证活性
Paraformaldehyde-fixed, paraffin embedded (human prostate); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (PLCZ1) Polyclonal Antibody, Unconjugated (TMAB-01549) at 1:200 overnight at 4°C, followed by a conjugated Goat Anti-Rabbit IgG antibody for 90 minutes, and DAPI for nucleus staining.
verifiedActivity
应用IFIHC-Fr
推荐剂量
IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Expressed specifically in testis and sperm. Weakly expressed in pancreatic-duct cells. Up-regulated in pancreatic-duct cells from patients with cystic fibrosis.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, PLCZ1 hydrolyzes PtdIns(4,5)P2 in a Ca2+-dependent manner. It triggers intracellular Ca2+ oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. PLCZ1 is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. It may exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.
抗原信息
免疫原
KLH conjugated synthetic peptide: human PLCZ1
抗原种属
Human
基因名称
PLCZ1
基因ID
89869
蛋白名称
1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase zeta-1
Uniprot ID
Q86YW0
研究领域
Metabolism of lipids and lipoproteins,Lipid metabolism
化学信息
分子量Theoretical: 70 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

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关键词

PLC-ζ-1PLC-zeta-1PLCZ 1PLC ζ1PLC zeta1Phospholipase C-ζ-1 (PLC-ζ-1)Phosphoinositide phospholipase C-ζ-15-bisphosphate phosphodiesterase ζ-11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase ζ-1
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