Powder: -20°C for 3 years | In solvent: -80°C for 1 year
KMG-104 is a fluorescent magnesium (Mg2+) probe known for its exceptional selectivity. It has been extensively utilized to investigate the mobilization of Mg2+ in the cytoplasm across different cell types.
产品描述 | KMG-104 is a fluorescent magnesium (Mg2+) probe known for its exceptional selectivity. It has been extensively utilized to investigate the mobilization of Mg2+ in the cytoplasm across different cell types. |
体外活性 | KMG-104 is useful for confocal laser scanning microscopy because it is excited at 490 nm, and emitted fluorescence around 510 nm. Fluorescent intensity of KMG-104 increases with [Mg] increase, and it shows no response to Na, K, and Ca; the dissociation constant (K d ) for Mg is 3 mM. KMG-104 is able to trace only [Mg] change inphysiological conditions[2]. PC12 cells are loaded with a novel Mg indicator KMG-104 and Ca indicator fura-2, and intracellular Mg is studied in the endoplasmic reticulums (ERs), mitochondria, and Mg-ATP[2]. |
分子量 | 435.339 |
分子式 | C23H11F2NO6 |
CAS No. | 852057-94-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
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