PSG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.2 kDa and the accession number is P11464-1.
生物活性 | Testing in progress |
产品描述 | PSG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.2 kDa and the accession number is P11464-1. |
种属 | Human |
表达系统 | HEK293 Cells |
标签 | C-hFc |
蛋白编号 | P11464-1 |
别名 | PSGIIA, PS-β-C/D, FL-NCA-1/2, PSBG1, PSG95, PS-beta-G-1, pregnancy specific β-1-glycoprotein 1, PS-β-G-1, PSBG-1, CD66f, pregnancy specific beta-1-glycoprotein 1, B1G1, SP1, PSGGA, DHFRP2, PBG1, PS-beta-C/D |
蛋白构建 | The Human PSG1 (NP_001171754.1) (Met1-Pro419) was expressed with the Fc region of Human IgG1 at the C-terminus. |
蛋白纯度 | > 85 % as determined by SDS-PAGE. |
分子量 | 70.2 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | Pregnancy-specific glycoproteins (PSGs) are a family of Ig-like proteins secreted by specialized placental cells. The PSG1 structure is composed of a single Ig variable region-like N-terminal domain and three Ig constant region-like domains termed A1, A2, and B2. Members of the human and murine PSG family have been shown to induce anti-inflammatory cytokines from monocytes and macrophages and to stimulate angiogenesis. Two distinct domains of PSG1 are involved in the regulation of TGF-beta1 and provide a mechanistic framework for how PSGs modulate the immunoregulatory environment at the maternal-fetal interface for successful pregnancy outcome. |
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PSG1 Protein, Human, Recombinant (hFc) PSBG 1 PSGIIA PS-β-C/D FL-NCA-1/2 PSG-95 pregnancy specific b-1-glycoprotein 1 PSBG1 SP-1 PBG-1 PSG95 SP 1 PS-beta-G-1 pregnancy specific β-1-glycoprotein 1 PS-β-G-1 PBG 1 PSBG-1 CD66f PS-b-C/D pregnancy specific beta-1-glycoprotein 1 PSG 95 B1G1 DHFRP 2 SP1 PSGGA DHFRP2 PBG1 PS-beta-C/D DHFRP-2 PS-b-G-1 recombinant recombinant-proteins proteins protein