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Anti-BMP-4 Antibody (3R788)

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产品编号 TMAH-00117
别名 ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B

Anti-BMP-4 Antibody (3R788) 是一种抗体,靶向 BMP-4。Anti-BMP-4 Antibody (3R788) 可用于 ELISA, WB, IF Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200。

Anti-BMP-4 Antibody (3R788)

Anti-BMP-4 Antibody (3R788)

Rating icon 还可以
产品编号 TMAH-00117 别名 ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B

Anti-BMP-4 Antibody (3R788) 是一种抗体,靶向 BMP-4。Anti-BMP-4 Antibody (3R788) 可用于 ELISA, WB, IF Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200。

规格价格库存数量
50 μL
¥ 1,300
5日内发货
100 μL
¥ 2,185
5日内发货
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产品介绍

生物活性
产品描述
Anti-BMP-4 Antibody (3R788) is an antibody targeting BMP-4. Anti-BMP-4 Antibody (3R788) can be used in ELISA, WB, IF Recommended dilution: WB:1:500-1:2000, IF:1:50-1:200.
别名ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B
Ig Type
Rabbit IgG
克隆号
3R788
交叉反应
Human
验证活性
1. Western Blot
-Positive WB detected in: Hela whole cell lysate
-All lanes: BMP4 antibody at 1:2000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 47 kDa
-Observed band size: 36-55 kDa
2. Immunofluorescence staining of Hela cell with TMAH-00117 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 508-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
应用
ELISA, WB, IF
推荐剂量
WB:1:500-1:2000; IF:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位Secreted, extracellular space, extracellular matrix.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction. Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. Once all three components are bound together in a complex at the cell surface, BMPR2 phosphorylates and activates BMPR1A. In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes. Can also signal through non-canonical BMP pathways such as ERK/MAP kinase, PI3K/Akt, or SRC cascades. For example, induces SRC phosphorylation which, in turn, activates VEGFR2, leading to an angiogenic response.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human BMP4
抗原种属
Human
基因ID
652
Uniprot ID
研究领域
Cancer, Cardiovascular, Developmental biology, Signal transduction, Stem cells
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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