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顶部生物活性储存和溶解信息计算器

Anti-BMP-4 Antibody (3R788)

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产品编号 TMAH-00117

别名 ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B

Anti-BMP-4 Antibody (3R788) 是一种抗体，靶向 BMP-4。Anti-BMP-4 Antibody (3R788) 可用于 ELISA,IF,WB。

Anti-BMP-4 Antibody (3R788)

Anti-BMP-4 Antibody (3R788)

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Rating icon 还可以
产品编号 TMAH-00117 别名 ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B

Anti-BMP-4 Antibody (3R788) 是一种抗体，靶向 BMP-4。Anti-BMP-4 Antibody (3R788) 可用于 ELISA,IF,WB。

规格价格库存数量
50 μL
¥ 1,300
5日内发货
100 μL
¥ 2,185
5日内发货
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产品介绍

生物活性
产品描述
Anti-BMP-4 Antibody (3R788) is an antibody targeting BMP-4. Anti-BMP-4 Antibody (3R788) can be used in ELISA,IF,WB.
别名ZYME, OFC11, MCOPS6, bone morphogenetic protein 4, BMP2B1, BMP2B
Ig Type
Rabbit IgG
克隆号
3R788
交叉反应
Human
验证活性
1. Western Blot
-Positive WB detected in: Hela whole cell lysate
-All lanes: BMP4 antibody at 1:2000
-Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution
-Predicted band size: 47 kDa
-Observed band size: 36-55 kDa
2. Immunofluorescence staining of Hela cell with TMAH-00117 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 508-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
应用ELISAIFWB
推荐剂量
WB:1:500-1:2000; IF:1:50-1:200.
抗体种类
Monoclonal
亚细胞定位Secreted, extracellular space, extracellular matrix.
组织特异性Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines.
构建方式Recombinant Antibody
纯化方式Affinity-chromatography
性状Liquid
缓冲液Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes, including neurogenesis, vascular development, angiogenesis and osteogenesis. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction. Initiates the canonical BMP signaling cascade by associating with type I receptor BMPR1A and type II receptor BMPR2. Once all three components are bound together in a complex at the cell surface, BMPR2 phosphorylates and activates BMPR1A. In turn, BMPR1A propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target genes. Can also signal through non-canonical BMP pathways such as ERK/MAP kinase, PI3K/Akt, or SRC cascades. For example, induces SRC phosphorylation which, in turn, activates VEGFR2, leading to an angiogenic response.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: Human BMP4
抗原种属
Human
基因名称
BMP4
基因ID
652
Uniprot ID
P12644
研究领域
Cancer, Cardiovascular, Developmental biology, Signal transduction, Stem cells
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

OFC-11OFC 11MCOPS-6MCOPS 6

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4个月前
5.0
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