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Anti-EPCR Antibody (7A928) 是一种 Rabbit 抗体,靶向 EPCR。Anti-EPCR Antibody (7A928) 可用于 ELISA。
Anti-EPCR Antibody (7A928) 是一种 Rabbit 抗体,靶向 EPCR。Anti-EPCR Antibody (7A928) 可用于 ELISA。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 μL | ¥ 2,284 | 5日内发货 |
产品描述 | Anti-EPCR Antibody (7A928) is a Rabbit antibody targeting EPCR. Anti-EPCR Antibody (7A928) can be used in ELISA. |
别名 | protein C receptor, endothelial |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 7A928 |
交叉反应 | Mouse |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Epcr / PROCR (rM Epcr / PROCR; TMPY-02487; Q64695; Met1-Ser214). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other animals after activated by binding to Endothelial protein C receptor (EPCR). Because of the EPCR is found primarily on endothelial cells (cells on the inside of blood vessels), activated protein C is found mainly near endothelial cells. Protein C is pleiotropic, with two main functions: anticoagulation and cytoprotection. Which function will be performed depending on whether or not protein C remains bind to EPCR after activated. The anticoagulation occurs when it does not. In this case, protein C functions as an anticoagulant by irreversibly proteolytically inactivating Factor Va and Factor VIIIa, turning them into Factor Vi and Factor VIIIi respectively. When still bound to EPCR, activated protein C performs its cytoprotective effects, acting on the effector substrate PAR-1, protease-activated receptor-1. To a degree, APC's anticoagulant properties are independent of its cytoprotective ones, in that expression of one pathway is not affected by the existence of the other. |
偶联 | Unconjugated |
免疫原 | Recombinant Mouse Epcr / PROCR Protein (TMPY-02487) |
抗原种属 | Mouse |
研究领域 | Serine Proteases and Regulators |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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