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Anti-EPCR Antibody (7A928)

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产品编号 TMAY-03488
别名 protein C receptor, endothelial

Anti-EPCR Antibody (7A928) 是一种 Rabbit 抗体,靶向 EPCR。Anti-EPCR Antibody (7A928) 可用于 ELISA。

Anti-EPCR Antibody (7A928)

Anti-EPCR Antibody (7A928)

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产品编号 TMAY-03488 别名 protein C receptor, endothelial

Anti-EPCR Antibody (7A928) 是一种 Rabbit 抗体,靶向 EPCR。Anti-EPCR Antibody (7A928) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,284
5日内发货
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产品介绍

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产品描述
Anti-EPCR Antibody (7A928) is a Rabbit antibody targeting EPCR. Anti-EPCR Antibody (7A928) can be used in ELISA.
别名protein C receptor, endothelial
Ig Type
Monoclonal Rabbit IgG
克隆号
7A928
交叉反应
Mouse
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse Epcr / PROCR (rM Epcr / PROCR; TMPY-02487; Q64695; Met1-Ser214).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Endothelial protein C receptor (EPCR), also known as activated protein C receptor (APC receptor) or PROCR, is a receptor for Protein C. Protein C plays an important role in many metabolism processes in humans and other animals after activated by binding to Endothelial protein C receptor (EPCR). Because of the EPCR is found primarily on endothelial cells (cells on the inside of blood vessels), activated protein C is found mainly near endothelial cells. Protein C is pleiotropic, with two main functions: anticoagulation and cytoprotection. Which function will be performed depending on whether or not protein C remains bind to EPCR after activated. The anticoagulation occurs when it does not. In this case, protein C functions as an anticoagulant by irreversibly proteolytically inactivating Factor Va and Factor VIIIa, turning them into Factor Vi and Factor VIIIi respectively. When still bound to EPCR, activated protein C performs its cytoprotective effects, acting on the effector substrate PAR-1, protease-activated receptor-1. To a degree, APC's anticoagulant properties are independent of its cytoprotective ones, in that expression of one pathway is not affected by the existence of the other.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Mouse Epcr / PROCR Protein (TMPY-02487)
抗原种属
Mouse
研究领域
Serine Proteases and Regulators
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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