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顶部生物活性储存和溶解信息计算器

Anti-OX40/TNFRSF4 Antibody (5W381)

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产品编号 TMAY-00886

别名 TXGP1L, tumor necrosis factor receptor superfamily, member 4, OX40, IMD16, CD134, ACT35

Anti-OX40/TNFRSF4 Antibody (5W381) 是一种 Mouse 抗体，靶向 OX40/TNFRSF4。Anti-OX40/TNFRSF4 Antibody (5W381) 可用于 ELISA。

Anti-OX40/TNFRSF4 Antibody (5W381)

Anti-OX40/TNFRSF4 Antibody (5W381)

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产品编号 TMAY-00886 别名 TXGP1L, tumor necrosis factor receptor superfamily, member 4, OX40, IMD16, CD134, ACT35

Anti-OX40/TNFRSF4 Antibody (5W381) 是一种 Mouse 抗体，靶向 OX40/TNFRSF4。Anti-OX40/TNFRSF4 Antibody (5W381) 可用于 ELISA。

规格价格库存数量
20 μL
¥ 790
5日内发货
100 μL
¥ 2,284
5日内发货
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产品介绍

生物活性
产品描述
Anti-OX40/TNFRSF4 Antibody (5W381) is a Mouse antibody targeting OX40/TNFRSF4. Anti-OX40/TNFRSF4 Antibody (5W381) can be used in ELISA.
别名TXGP1L, tumor necrosis factor receptor superfamily, member 4, OX40, IMD16, CD134, ACT35
Ig Type
Mouse IgG1
克隆号
5W381
交叉反应
Human
特异性
Human OX40/TNFRSF4
应用ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human OX40/TNFRSF4/CD134 (rh OX40/TNFRSF4/CD134; TMPY-01423; NP_003318.1; Met1-Ala216). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景OX40 (CD134) and its binding partner, OX40L (CD252), are members of the tumor necrosis factor receptor/tumor necrosis factor superfamily, is known to break an existing state of tolerance in malignancies, leading to a reactivation of antitumor immunity. The interaction between OX40 and OX40L plays an important role in antigen-specific T-cell expansion and survival. OX40 and OX40L also regulate cytokine production from T cells, antigen-presenting cells, natural killer cells, and natural killer T cells, and modulate cytokine receptor signaling. In line with these important modulatory functions, OX40-OX40L interactions have been found to play a central role in the development of multiple inflammatory and autoimmune diseases, making them attractive candidates for intervention in the clinic. Conversely, stimulating OX40 has shown it to be a candidate for therapeutic immunization strategies for cancer and infectious disease.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human OX40/TNFRSF4/CD134 Protein (TMPY-01423)
抗原种属
Human
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

关键词

OX-40OX 40IMD-16IMD 16CD-134CD 134ACT-35ACT 35

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