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Rift valley fever virus (RVFV) (strain ZH-548 M12) Non-structural protein S (His & Myc)

Synonyms: NSs, Non-structural protein S
货号 TMPH-03415 一键复制产品信息
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Plays a role in the escape of host innate immune response by promoting the degradation of host EIF2AK2/PKR and inhibiting host transcription. Cytoplasmic NSs interacts with host FBXW11 to degrade PKR whereas nuclear pool binds to host FBXO3 to target TFIIH subunit GTF2H1 for proteasomal degradation. Forms filaments in the nucleus that may sequester NSs binding partners, causing cell cycle arrest. Rift valley fever virus (RVFV) (strain ZH-548 M12) Non-structural protein S (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.3 kDa and the accession number is P21698.

Rift valley fever virus (RVFV) (strain ZH-548 M12) Non-structural protein S (His & Myc)

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货号 TMPH-03415

别名 NSs, Non-structural protein S

Plays a role in the escape of host innate immune response by promoting the degradation of host EIF2AK2/PKR and inhibiting host transcription. Cytoplasmic NSs interacts with host FBXW11 to degrade PKR whereas nuclear pool binds to host FBXO3 to target TFIIH subunit GTF2H1 for proteasomal degradation. Forms filaments in the nucleus that may sequester NSs binding partners, causing cell cycle arrest. Rift valley fever virus (RVFV) (strain ZH-548 M12) Non-structural protein S (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.3 kDa and the accession number is P21698.

Rift valley fever virus (RVFV) (strain ZH-548 M12) Non-structural protein S (His & Myc)
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规格价格库存数量
5 μg
¥ 825
3日内发货
10 μg
¥ 1,360
3日内发货
20 μg
¥ 2,290
3日内发货
50 μg
¥ 3,460
3日内发货
100 μg
¥ 4,750
现货
200 μg
¥ 6,830
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500 μg
¥ 10,800
20日内发货
1 mg
¥ 16,000
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纯度: Greater than 85% as determined by SDS-PAGE.
颜色: 白色
性状: Lyophilized powder
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资源下载:
COA重组蛋白用户指南

产品介绍

生物活性
产品描述
Plays a role in the escape of host innate immune response by promoting the degradation of host EIF2AK2/PKR and inhibiting host transcription. Cytoplasmic NSs interacts with host FBXW11 to degrade PKR whereas nuclear pool binds to host FBXO3 to target TFIIH subunit GTF2H1 for proteasomal degradation. Forms filaments in the nucleus that may sequester NSs binding partners, causing cell cycle arrest. Rift valley fever virus (RVFV) (strain ZH-548 M12) Non-structural protein S (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.3 kDa and the accession number is P21698.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Plays a role in the escape of host innate immune response by promoting the degradation of host EIF2AK2/PKR and inhibiting host transcription. Cytoplasmic NSs interacts with host FBXW11 to degrade PKR whereas nuclear pool binds to host FBXO3 to target TFIIH subunit GTF2H1 for proteasomal degradation. Forms filaments in the nucleus that may sequester NSs binding partners, causing cell cycle arrest.
种属
RVFV
表达系统
E. coli
标签N-10xHis, C-Myc
蛋白编号P21698
氨基酸序列MDYFPVISVDLQSGRRVVSVEYFRGDGPPRIPYSMVGPCCVFLMHHRPSHEVRLRFSDFYNVGEFPYRVGLGDFASNVAPPPAKPFQRLIDLIGHMTLSDFTRFPNLKEAISWPLGEPSLAFFDLSSTRVHRNDDIRRDQIATLAMRSCKITNDLEDSFAGLHRMIATEAILRGIDLCLLPGFDLMYEVAHVQCVRLLQAAKEDISNAVVPNSALIVLMEESLMLRSSLPSMMGRNNWIPVIPPIPDVEMESEEESDDDGFVEVD
蛋白构建1-265 aa
蛋白纯度
> 85% as determined by SDS-PAGE.
Rift valley fever virus (RVFV) (strain ZH-548 M12) Non-structural protein S (His & Myc)
缓冲液If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
复溶方法Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名NSs, Non-structural protein S
内毒素< 1.0 EU/μg of the protein as determined by the LAL method.
化学信息
分子量37.3 kDa (predicted)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

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剂量转换

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技术支持

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