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Anti-CASP9 Antibody (8M475)
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产品编号 TMAC-03429
别名 MCH6, ICE-like apoptotic protease 6, ICE-LAP6, EC 3.4.22.62, Caspase-9, Caspase9, CASP-9, Apoptotic protease-activating factor 3, Apoptotic protease Mch-6, APAF-3
Anti-CASP9 Antibody (8M475) 是一种 Rabbit 抗体，靶向 CASP9。Anti-CASP9 Antibody (8M475) 可用于 WB,IHC,FCM。
Anti-CASP9 Antibody (8M475)
Anti-CASP9 Antibody (8M475)
还可以产品编号 TMAC-03429 别名 MCH6, ICE-like apoptotic protease 6, ICE-LAP6, EC 3.4.22.62, Caspase-9, Caspase9, CASP-9, Apoptotic protease-activating factor 3, Apoptotic protease Mch-6, APAF-3
Anti-CASP9 Antibody (8M475) 是一种 Rabbit 抗体，靶向 CASP9。Anti-CASP9 Antibody (8M475) 可用于 WB,IHC,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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| 产品描述 | Anti-CASP9 Antibody (8M475) is a Rabbit antibody targeting CASP9. Anti-CASP9 Antibody (8M475) can be used in WB,IHC,FCM. |
| 别名 | MCH6, ICE-like apoptotic protease 6, ICE-LAP6, EC 3.4.22.62, Caspase-9, Caspase9, CASP-9, Apoptotic protease-activating factor 3, Apoptotic protease Mch-6, APAF-3 |
| Ig Type | IgG |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of pro Caspase 9 on Hela cells lysates using anti-pro Caspase 9 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-pro Caspase 9 antibody. Counter stained with hematoxylin. 3. Flow cytometric analysis of Jurkat cells with pro Caspase 9 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200; FCM: 1:10-50 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, Ced-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6, caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9 and caspase-10. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Poly(ADP-ribose) polymerase plays an integral role in surveying for DNA mutations and double strand breaks. Caspase-3, caspase-7 and caspase-9, but not caspase-1, have been shown to cleave the nuclear protein PARP into an apoptotic fragment. Caspase-6, but not caspase-3, has been shown to cleave the nuclear lamins, which are critical to maintaining the integrity of the nuclear envelope and cellular morphology. Caspase-10 has been shown to activate caspase-3 and caspase-7 in response to apoptotic stimuli. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 46 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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