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顶部生物活性储存和溶解信息计算器

Anti-IL-9 Antibody (2Q145)

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产品编号 TMAY-03572

别名 白细胞介素, P40, interleukin 9, Il-9

Anti-IL-9 Antibody (2Q145) 是一种 Rabbit 抗体，靶向 IL-9。Anti-IL-9 Antibody (2Q145) 可用于 ELISA。

Anti-IL-9 Antibody (2Q145)

Anti-IL-9 Antibody (2Q145)

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产品编号 TMAY-03572 别名 白细胞介素, P40, interleukin 9, Il-9

Anti-IL-9 Antibody (2Q145) 是一种 Rabbit 抗体，靶向 IL-9。Anti-IL-9 Antibody (2Q145) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,689
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-9 Antibody (2Q145) is a Rabbit antibody targeting IL-9. Anti-IL-9 Antibody (2Q145) can be used in ELISA.
别名白细胞介素, P40, interleukin 9, Il-9
Ig Type
Rabbit IgG
克隆号
2Q145
交叉反应
Mouse
特异性
Mouse IL-9
应用ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-9 (rM IL-9; TMPY-05221; NP_032399.1; Met1-Pro144).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Interleukin 9, also known as IL-9, is a cytokine (cell signaling molecule) belonging to the group of interleukins. IL-9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL-9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. IL-9 is a key molecule that affects the differentiation of TH17 cells and Treg function. IL-9 predominantly produced by TH17 cells synergizes with TGF-β1 to differentiate naive CD4+ T cells into TH17 cells, while IL-9 secretion by TH17 cells is regulated by IL-23. Interestingly, IL-9 enhances the suppressive functions of FoxP3+ CD4+ Treg cells in vitro, and the absence of IL-9 signaling weakens the suppressive activity of nTregs in vivo, leading to an increase in effector cells and worsening of experimental autoimmune encephalomyelitis. The mechanism of IL-9 effects on TH17 and Tregs is through activation of STAT3 and STAT5 signaling. Our findings highlight the role of IL-9 as a regulator of pathogenic versus protective mechanisms of immune responses.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Mouse IL-9 Protein (TMPY-05221)
抗原种属
Mouse
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

P-40P 40

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