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Anti-DPP4/CD26 Antibody-PE (6M894)
还可以产品编号 TMAY-01062P
Anti-DPP4/CD26 Antibody-PE (6M894) 是一种 PE-conjugated Mouse 抗体，靶向 DPP4/CD26。Anti-DPP4/CD26 Antibody-PE (6M894) 可用于 FCM。
Anti-DPP4/CD26 Antibody-PE (6M894)
Anti-DPP4/CD26 Antibody-PE (6M894)
还可以产品编号 TMAY-01062P
Anti-DPP4/CD26 Antibody-PE (6M894) 是一种 PE-conjugated Mouse 抗体，靶向 DPP4/CD26。Anti-DPP4/CD26 Antibody-PE (6M894) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-DPP4/CD26 Antibody-PE (6M894) is a PE-conjugated Mouse antibody targeting DPP4/CD26. Anti-DPP4/CD26 Antibody-PE (6M894) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 6M894 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human CD26(DPP4) expression on human whole blood lymphocytes. Cells were stained with PE-conjugated anti-Human CD26(DPP4). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | 10 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human DPP4 / CD26 (rh DPP4 / CD26; TMPY-00779; NP_001926.2; Asn29-Pro766) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the N-terminus of polypeptides, such as chemokines, neuropeptides, and peptide hormones. The enzyme is a type II transmembrane glycoprotein, expressed on the surface of many cell types. It is also present in serum and other body fluids in a truncated form (sCD26/DPPIV). The soluble CD26 (sCD26) as a tumour marker for the detection of colorectal cancer (CRC) and advanced adenomas. As both a regulatory enzyme and a signalling factor, DPP4 has been evaluated and described in many studies. DPP4 inhibition results in increased blood concentration of the incretin hormones glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP). This causes an increase in glucose-dependent stimulation, resulting in a lowering of blood glucose levels. Recent studies have shown that DPP4 inhibitors can induce a significant reduction in glycosylated haemoglobin (HbA(1c)) levels, either as monotherapy or as a combination with other antidiabetic agents. Research has also demonstrated that DPP4 inhibitors portray a very low risk of hypoglycaemia development, and are a new pharmacological class of drugs for treating Type 2 diabetes. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC/FITC |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human DPP4 / CD26 protein (TMPY-00779) |
| 抗原种属 | Human |
| 研究领域 | Serine Proteases and Regulators |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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