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Anti-KIR5.1 Polyclonal Antibody

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货号 TMAB-08077

Anti-KIR5.1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KIR5.1。Anti-KIR5.1 Polyclonal Antibody 可用于 ELISA,WB。

Anti-KIR5.1 Polyclonal Antibody

Anti-KIR5.1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08077

Anti-KIR5.1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 KIR5.1。Anti-KIR5.1 Polyclonal Antibody 可用于 ELISA,WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-KIR5.1 Polyclonal Antibody is a Rabbit antibody targeting KIR5.1. Anti-KIR5.1 Polyclonal Antibody can be used in ELISA,WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Horse,Rabbit)
应用ELISAWB
推荐剂量
ELISA: 1:5000-10000; WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane; Multi pass membrane protein.
组织特异性Highly expressed in kidney, pancreas and thyroid gland.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The KIR family of potassium channels possess a greater tendency to allow potassium to flow into the cell rather than out of it. Kir4.1, also known as Kir1.2, is highly expressed in brain including glial cells, astrocytes and cortical neurons. Kir4.1 is also expressed in myelin-synthesizing oligodendrocytes and is crucial to myelination in the developing nervous system. The gene encoding human Kir4.1 maps to chromosome 1. Kir4.2, also known as Kir1.3, is expressed in kidney, lung, heart, thymus and thyroid during development. The gene encoding human Kir4.2 maps to chromosome 21 in the Down syndrome chromosome region 1, and Kir4.2 may play a role in the pathogenesis of Down’s syndrome. Kir 5.1 forms functional channels only by coexpression with either Kir4.1 or Kir4.2 in the kidney and pancreas. The gene encoding human Kir5.1 maps to chromosome 17.
抗原信息
免疫原
KLH conjugated synthetic peptide: human KIR5.1
抗原种属
Human
基因名称
KCNJ16
基因ID
蛋白名称
Inward rectifier potassium channel 16
Uniprot ID
功能
KIR5.1 is one of 20 members of the inwardly rectifying potassium (Kir) channel family. Due to its expression in kidney, pancreas and thyroid gland, it has been suggested that human KIR5.1 may be involved in the regulation of fluid and pH balance, thus making it a potential therapeutic target for hypertension, renal failure, or pancreatic disease.
化学信息
分子量Theoretical: 48 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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