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Anti-BAIAP2 Polyclonal Antibody

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货号 TMAB-03019

Anti-BAIAP2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 BAIAP2。Anti-BAIAP2 Polyclonal Antibody 可用于 WB。

Anti-BAIAP2 Polyclonal Antibody

Anti-BAIAP2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-03019

Anti-BAIAP2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 BAIAP2。Anti-BAIAP2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-BAIAP2 Polyclonal Antibody is a Rabbit antibody targeting BAIAP2. Anti-BAIAP2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell Membrane and Cytoplasmic.
组织特异性Isoform 1 and isoform 4 are expressed almost exclusively in brain. Isoform 4 is barely detectable in placenta, prostate and testis. A short isoform is ubiquitous, with the highest expression in liver, prostate, testis and placenta.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. Alternative splicing of the end of this gene results in three products of undetermined function.
抗原信息
免疫原
KLH conjugated synthetic peptide: human IRS P53
抗原种属
Human
基因名称
BAIAP2
基因ID
蛋白名称
Brain-specific angiogenesis inhibitor 1-associated protein 2
Uniprot ID
功能
Adapter protein that links membrane-bound small G-proteins to cytoplasmic effector proteins. Necessary for CDC42-mediated reorganization of the actin cytoskeleton and for RAC1-mediated membrane ruffling. Involved in the regulation of the actin cytoskeleton by WASF family members and the Arp2/3 complex. Plays a role in neurite growth. Acts syngeristically with ENAH to promote filipodia formation.
化学信息
分子量Theoretical: 61 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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