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Anti-TXNL4B Antibody (5F871) 是一种 Rabbit 抗体,靶向 TXNL4B。Anti-TXNL4B Antibody (5F871) 可用于 ELISA。
Anti-TXNL4B Antibody (5F871) 是一种 Rabbit 抗体,靶向 TXNL4B。Anti-TXNL4B Antibody (5F871) 可用于 ELISA。
产品描述 | Anti-TXNL4B Antibody (5F871) is a Rabbit antibody targeting TXNL4B. Anti-TXNL4B Antibody (5F871) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 5F871 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Dim2 / TXNL4B (rh Dim2 / TXNL4B; TMPY-02723; Q9NX01; Met1-Ile149). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Dim2, also known as TXNL4B, is a member of the DIM1 family. The Dim protein family is composed of two classes, Dim1and Dim2, which share a common thioredoxin-like fold. They were originally identified for their role in cell cycle progression and have been found to interact with Prp6, an essential component of the spliceosome, which forms the bridge of U4/U6.U5-tri-snRNP. Despite their biological and structural similarities, Dim1 and Dim2 proteins differ in many aspects. Dim1 bears distinctive structural motifs responsible for its interaction with other spliceosome components. Dim2 forms homodimers and contains specific domains required for its interactions with partners. This originality suggests that although both proteins are involved in pre-mRNA splicing, they are likely to be involved in different biological pathways. Dim2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 185 amino acids and having a molecular mass of 21.1kDa. It is fused to a 36 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Dim2 has a vital role in pro-mRNA splicing. Dim2 is required in cell cycle progression for S/G2 transition and interacts with PRPF6 subunit of the spliceosome. |
偶联 | Unconjugated |
免疫原 | Recombinant Human Dim2 / TXNL4B protein (TMPY-02723) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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