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Anti-KIF11 Antibody (2W383) 是一种 Rabbit 抗体,靶向 KIF11。Anti-KIF11 Antibody (2W383) 可用于 WB,IP。
Anti-KIF11 Antibody (2W383) 是一种 Rabbit 抗体,靶向 KIF11。Anti-KIF11 Antibody (2W383) 可用于 WB,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-KIF11 Antibody (2W383) is a Rabbit antibody targeting KIF11. Anti-KIF11 Antibody (2W383) can be used in WB,IP. |
别名 | TRIP-5, TRIP5, TR-interacting protein 5, Thyroid receptor-interacting protein 5, KNSL1, Kinesin-related motor protein Eg5, Kinesin-like spindle protein HKSP, Kinesin-like protein KIF11, Kinesin-like protein 1, KIF 11, EG5 |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of Eg5 on different cell lysates using anti-Eg5 antibody at 1/500 dilution. Positive control: Lane 1: 293, Lane 2: A431, Lane 3: Jurkat. |
应用 | |
推荐剂量 | WB: 1:500-2000; IP: 1:10-50 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Eukaryotes contain a superfamily of microtubule-based motor proteins comprising kinesin and a number of related proteins that are thought to participate in various forms of intracellular motility, including cell division and organelle transport. KIF11(also known as kinesin family member 11, Eg5 or TRIP5) is a slow, plus-end-directed microtubule-based motor of the BimC kinesin family that is essential for bipolar spindle formation during eukaryotic cell division. When the expression of KIF11 is blocked, centrosome migration halts and cells are arrested in mitosis with monoastral microtubule arrays. KIF11 is phosphorylated on serine during S phase and on both serine and Thr 927 during mitosis, which regulates the association of Eg5 with the spindle apparatus (probably during early prophase). KIF11 is also known to be a member of the thyroid receptor interacting protein (Trip) family, and interacts with the thyroid hormone receptor only in the presence of thyroid hormone. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 119 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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