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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-IBTK Polyclonal Antibody

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货号 TMAB-07471

Anti-IBTK Polyclonal Antibody 是一种 Rabbit 抗体，靶向 IBTK。Anti-IBTK Polyclonal Antibody 可用于 WB。

Anti-IBTK Polyclonal Antibody

Anti-IBTK Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-07471

Anti-IBTK Polyclonal Antibody 是一种 Rabbit 抗体，靶向 IBTK。Anti-IBTK Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-IBTK Polyclonal Antibody is a Rabbit antibody targeting IBTK. Anti-IBTK Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Pig)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Membrane; Peripheral membrane protein. Note=Translocates to the plasma membrane upon IgM stimulation.Isoform 2: Nucleus.
组织特异性Expressed in DeFew, HEK293T, HeLa and in Jurkat, MC3 and NB4 lymphoid cells (at protein level). Isoform 1 is the predominant isoform expressed in all examined tissues and cell lines. Highly expressed in hemopoietic tissues (fetal liver, spleen, lymph node, thymus, peripheral blood leukocytes and bone marrow). Weakly or not expressed in other tissues.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景IBTK is a encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.
抗原信息
免疫原
KLH conjugated synthetic peptide: human IBTK
抗原种属
Human
基因名称
IBTK
基因ID
25998
蛋白名称
Inhibitor of Bruton tyrosine kinase
Uniprot ID
Q9P2D0
功能
Acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development. Down-regulates BTK kinase activity, leading to interference with BTK-mediated calcium mobilization and NF-kappa-B-driven transcription.
化学信息
分子量Theoretical: 150 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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