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Anti-Syndecan-1 Antibody-PE (1I989)
还可以产品编号 TMAY-01863P
Anti-Syndecan-1 Antibody-PE (1I989) 是一种 PE-conjugated Rabbit 抗体，靶向 Syndecan-1。Anti-Syndecan-1 Antibody-PE (1I989) 可用于 FCM。
Anti-Syndecan-1 Antibody-PE (1I989)
Anti-Syndecan-1 Antibody-PE (1I989)
还可以产品编号 TMAY-01863P
Anti-Syndecan-1 Antibody-PE (1I989) 是一种 PE-conjugated Rabbit 抗体，靶向 Syndecan-1。Anti-Syndecan-1 Antibody-PE (1I989) 可用于 FCM。
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产品介绍
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偶联与修饰
抗原信息
| 产品描述 | Anti-Syndecan-1 Antibody-PE (1I989) is a PE-conjugated Rabbit antibody targeting Syndecan-1. Anti-Syndecan-1 Antibody-PE (1I989) can be used in FCM. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 1I989 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human SDC1(CD138) expression on RPMI8226 cells. Cells were stained with PE-conjugated anti-Human SDC1(CD138). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| 应用 | FCM |
| 推荐剂量 | 5 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human Syndecan-1/CD138/SDC1 (rh Syndecan-1/CD138/SDC1; TMPY-01630; NP_002988.3; Met1-Glu251) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | Syndecan-1 also known as SDC1 and CD138, is the most extensively studied member of the syndecan family. It is found mainly in epithelial cells, but its expression is developmentally regulated during embryonic development. Syndecan-1/SDC1/CD138 has been shown to mediate cell adhesion to several ECM molecules, and to act as a coreceptor for fibroblast growth factors, potent angiogenic growth factors involved also in differentiation. Syndecan-1/SDC1/CD138 expression is reduced during malignant transformation of various epithelia, and this loss correlates with the histological differentiation grade of squamous cell carcinomas, lacking from poorly differentiated tumours. In squamous cell carcinomas of the head and neck, positive syndecan-1 expression correlates with a more favourable prognosis. Experimental studies on the role of Syndecan-1 in malignant transformation have shown that Syndecan-1/SDC1/CD138 expression is associated with the maintenance of epithelial morphology, anchorage-dependent growth and inhibition of invasiveness in vitro. |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC/PerCP/FITC |
| 可提供抗体种类 | 5 |
| 免疫原 | Recombinant Human Syndecan-1/CD138/SDC1 Protein (TMPY-01630) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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