RGMB Protein, Human, Recombinant (hFc)

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SPR兼容缓冲液

产品编号 TMPY-07146

RGMB Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q6NW40.

RGMB Protein, Human, Recombinant (hFc)

一键复制产品信息

SPR兼容缓冲液

产品编号 TMPY-07146

RGMB Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q6NW40.

规格	价格	库存
5 μg	¥ 493	6-8日内发货
10 μg	¥ 790	6-8日内发货
20 μg	¥ 1,330	5日内发货
50 μg	¥ 2,580	5日内发货
100 μg	¥ 5,170	5日内发货
200 μg	¥ 7,600	5日内发货
500 μg	¥ 15,300	5日内发货
1 mg	¥ 29,800	5日内发货

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产品信息

生物活性	Immobilized BMP4 Protein, Human, Recombinant (E399D) (Cat#TMPY-06842) at 2 μg/mL (100 μL/well) can bind RGMB Protein, Human, Recombinant (hFc) (Cat#TMPY-07146) with a linear range of 0.16-4 ug/mL.
产品描述	RGMB Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q6NW40.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	Q6NW40
别名	FLJ90406,DRAGON
蛋白构建	A DNA sequence encoding the Human RGMB (NP_001012779.2) (Met1-Asn413) was expressed with the Fc region of human IgG1 at the C-terminus.
蛋白纯度	≥ 95% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC.
分子量	67.26 kDa (predicted); 63.2 kDa and 20 kDa (reducing contition)
内毒素	< 1.0 EU per μg protein as determined by the LAL method.
缓冲液	Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
复溶方法	Please refer to the lot-specific COA.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	RGMB was knocked down in breast cancer cells by way of an anti-RGMB ribozyme transgene. Knockdown of RGMB resulted in enhanced capacities of proliferation, adhesion, and migration in breast cancer cells. Further investigations demonstrated RGMB knockdown resulted in a reduced expression and activity of Caspase-3, accompanied with better survival in RGMB knockdown cells under serum starvation, which might be induced by its repression on MAPK JNK pathway. That RGMB may act as a negative regulator in breast cancer through BMP signaling.