Name: Ampyrone
Brand: TargetMol
SKU: T0050
Price: 150 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

500 mg

¥ 163

In stock

1 g

¥ 247

In stock

5 g

¥ 572

In stock

10 g

¥ 837

In stock

1 mL x 10 mM (in DMSO)

¥ 150

In stock

产品介绍

生物活性

产品描述	Ampyrone (4-Aminoantipyrine) is a reagent for glucose determination in the presence of peroxidase and phenol.
体外活性	The level of glutathione(GSH) in single erythrocytes is impacted slightly at low AAP(4-aminoantipyrine) concentrations probably due to the protection of glutathione reductase. When AAP concentration further increases, AAP has a significant influence on GSH[2].
体内活性	4-aminoantipyrine (4-AA) is not genotoxic and mutagenic in vivo, it can interfere with DNA damaging agents biological activities and may reduce the effectiveness of DNA damage-based chemotherapy[3].
细胞实验	Erythrocytes in PBS are incubated for 2 h at ambient temperature (without mixing) with AAP in concentrations from 1 × 10−6 mol/L to 1 × 10−3 mol/L. Sample of erythrocytes without AAP is used as control. After the exposure of AAP, erythrocytes are washed with borate buffer (pH 9.0) 2 times by centrifuging and determined for GSH. (Only for Reference)
别名	Solnapyrin-A, NSC 60242, Minoazophene, Aminoantipyrin, 4-氨基安替比林, 4-Aminoantipyrine

化学信息

分子量	203.24
分子式	C₁₁H₁₃N₃O
CAS No.	83-07-8
Smiles	CS(=O)(=O)N(CC(O)=O)C1=CC(F)=CC=C1
密度	0.8 g/cm3
颜色	Yellow
物理性状	Solid

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

Ethanol: 40 mg/mL (196.81 mM), Sonication is recommended.

H2O: 37 mg/mL (182.05 mM), Sonication is recommended.

溶液配制表

H2O/Ethanol

	1mg	5mg	10mg	50mg
1 mM	4.9203 mL	24.6015 mL	49.2029 mL	246.0146 mL
5 mM	0.9841 mL	4.9203 mL	9.8406 mL	49.2029 mL
10 mM	0.4920 mL	2.4601 mL	4.9203 mL	24.6015 mL
20 mM	0.2460 mL	1.2301 mL	2.4601 mL	12.3007 mL
50 mM	0.0984 mL	0.4920 mL	0.9841 mL	4.9203 mL
100 mM	0.0492 mL	0.2460 mL	0.4920 mL	2.4601 mL

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， TargetMol | Animal experiments

一共给药动物 10 只 ，您使用的配方为 5% TargetMol | reagent

DMSO+ 30%PEG300+ 5%Tween 80 + 60%Saline/PBS/ddH₂O，那么您的工作液浓度为 2 mg/mL 。

母液配置方法: 2 mg 药物溶于 50 μLDMSO TargetMol | reagent

（母液浓度为 40 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法: 取 50μLDMSO TargetMol | reagent

母液，添加 300 μLPEG300 TargetMol | reagent

混匀澄清，再加 50μLTween 80, 混匀澄清，再加 600μLSaline/PBS/ddH₂O TargetMol | reagent

混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO， PEG300/ PEG400， Tween 80， SBE-β-CD，玉米油等，均可在TargetMol网站点击购买。

Ampyrone

Ampyrone

产品介绍

计算器

体内实验配液计算器

剂量转换

SCI 文献

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