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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-HspBP1 Polyclonal Antibody

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货号 TMAB-07366

Anti-HspBP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HspBP1。Anti-HspBP1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-HspBP1 Polyclonal Antibody

Anti-HspBP1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07366

Anti-HspBP1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 HspBP1。Anti-HspBP1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-HspBP1 Polyclonal Antibody is a Rabbit antibody targeting HspBP1. Anti-HspBP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Ubiquitous.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Hsp70-interacting protein (HspBP1) belongs to a family of eukaryotic proteins identified as nucleotide exchange factors for Hsp70, which exhibit varying degrees of compartment and species specificity. HspBP1 interferes with the CHIP-induced degradation of immature forms of the cystic fibrosis transmembrane conductance regulator (CFTR) and stimulates CFTR maturation. HspBP1 binds to Hsp70, inhibits its activity and promotes dissociation of nucleotides from the Hsp70 ATPase domain. It is a protein mainly expressed in heart and skeletal muscle.
抗原信息
免疫原
KLH conjugated synthetic peptide: human HspBP1
抗原种属
Human
基因名称
HSPBP1
基因ID
23640
蛋白名称
Hsp70-binding protein 1
Uniprot ID
Q9NZL4
功能
Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.
化学信息
分子量Theoretical: 39 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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