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Anti-PI 3 Kinase p110 delta Antibody (6K824) 是一种 Rabbit 抗体,靶向 PI 3 Kinase p110 delta。Anti-PI 3 Kinase p110 delta Antibody (6K824) 可用于 WB,IHC。
Anti-PI 3 Kinase p110 delta Antibody (6K824) 是一种 Rabbit 抗体,靶向 PI 3 Kinase p110 delta。Anti-PI 3 Kinase p110 delta Antibody (6K824) 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,495 | 5日内发货 | |
100 μL | ¥ 2,480 | 5日内发货 |
产品描述 | Anti-PI 3 Kinase p110 delta Antibody (6K824) is a Rabbit antibody targeting PI 3 Kinase p110 delta. Anti-PI 3 Kinase p110 delta Antibody (6K824) can be used in WB,IHC. |
别名 | PtdIns-3-kinase subunit p110-delta, PtdIns-3-kinase subunit delta, PtdIns 3 kinase subunit p110 delta, PtdIns 3 kinase p110, PK3CD_HUMAN, PK3CD, PIK3R1, Pik3cd, PI3-kinase subunit delta, PI3K-delta, PI3Kdelta, PI3K, PI3 kinase p110 subunit delta, PI 3 Kinase p110 δ, PI 3 Kinase p110 d, Phosphoinositide 3 kinase, catalytic, delta polypeptide variant p37delta, Phosphoinositide 3 kinase catalytic delta polypeptide, Phosphoinositide 3 kinase C, Phosphoinositide 3 kinase B, Phosphatidylinositol-4, Phosphatidylinositol 45 bisphosphate 3 kinase catalytic subunit delta isoform, Phosphatidylinositol 4,5 bisphosphate 3 kinase, catalytic subunit delta, Phosphatidylinositol 4,5 bisphosphate 3 kinase 110 kDa catalytic subunit delta, Phosphatidylinositol 4 5 bisphosphate 3 kinase catalytic subunit delta isoform, Phosphatidylinositol 3 kinase catalytic delta polypeptide, p85-ALPHA, p110dp85a, p110delta, p110d, IMD14, GRB1, APDS, 5-bisphosphate 3-kinase catalytic subunit delta isoform, 5-bisphosphate 3-kinase 110 kDa catalytic subunit delta |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of PI 3 Kinase p110 delta on mouse spleen tissue lysate using anti-PI 3 Kinase p110 delta antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-PI 3 Kinase p110 delta antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-PI 3 Kinase p110 delta antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:500; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85α and p85β), each possessing one SH3 and two SH2 domains. Various p110 forms have been identified. p110α and p110β interact with p85α, and p110α has also been shown to interact with p85β in vitro. It has been shown to bind p85α and β, but it apparently does not phosphorylate these subunits. p110δ has the capacity to autophosphorylate and results in the nearly complete inactivation of the lipid kinase activity. Interestingly, p110γ does not interact with the p85 subunits and has been shown to be activated by α and βγ heterotrimeric G proteins. Two p110δ isoforms have been identified and are widely expressed. Isoform 1 is expressed predominantly in leukocytes while isoform 2 is expressed in normal thymus, lung and spleen tissues. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 110 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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