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Anti-DRAK2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 DRAK2。Anti-DRAK2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。
Anti-DRAK2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 DRAK2。Anti-DRAK2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-DRAK2 Polyclonal Antibody is a Rabbit antibody targeting DRAK2. Anti-DRAK2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| 反应种属 | Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| 应用 | IHC-PIHC-FrICC/IFIF |
| 推荐剂量 | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Nucleus. Cell membrane. Endoplasmic reticulum-Golgi intermediate compartment. Note=Colocalizes with STK17B at the plasma membrane. |
| 组织特异性 | Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase related apoptosis inducing protein kinases). DRAKs contain an N terminal kinase domain and a C terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues. |
| 免疫原 | KLH conjugated synthetic peptide: human DRAK2 |
| 抗原种属 | Human |
| 基因名称 | STK17B |
| 基因ID | |
| 蛋白名称 | Serine/threonine-protein kinase 17B |
| Uniprot ID | |
| 功能 | Acts as a positive regulator of apoptosis. |
| 分子量 | Theoretical: 42 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |