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Anti-DRAK2 Polyclonal Antibody

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货号 TMAB-05314

Anti-DRAK2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 DRAK2。Anti-DRAK2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

Anti-DRAK2 Polyclonal Antibody

Anti-DRAK2 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05314

Anti-DRAK2 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 DRAK2。Anti-DRAK2 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-DRAK2 Polyclonal Antibody is a Rabbit antibody targeting DRAK2. Anti-DRAK2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
反应种属
Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
应用IHC-PIHC-FrICC/IFIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cell membrane. Endoplasmic reticulum-Golgi intermediate compartment. Note=Colocalizes with STK17B at the plasma membrane.
组织特异性Highly expressed in placenta, lung, pancreas. Lower levels in heart, brain, liver, skeletal muscle and kidney.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as ASK1 and RIP, are mediators of apoptosis. Two novel serine/threonine kinases that induce apoptosis were recently identified and designated DRAK1 and DRAK2 (for DAP kinase related apoptosis inducing protein kinases). DRAKs contain an N terminal kinase domain and a C terminal regulation domain. Overexpression of DRAK2 induces apoptosis. DRAKs have high sequence homology to DAP and ZIP kinases, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. DRAK2 is located in nucleus and the messenger RNA was ubiquitously expressed in human tissues.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DRAK2
抗原种属
Human
基因名称
STK17B
基因ID
蛋白名称
Serine/threonine-protein kinase 17B
Uniprot ID
功能
Acts as a positive regulator of apoptosis.
化学信息
分子量Theoretical: 42 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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