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Anti-ROR gamma T Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ROR gamma T。Anti-ROR gamma T Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。
Anti-ROR gamma T Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ROR gamma T。Anti-ROR gamma T Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,175 | 5日内发货 | |
100 μL | ¥ 1,960 | 5日内发货 | |
200 μL | ¥ 2,795 | 5日内发货 |
产品描述 | Anti-ROR gamma T Polyclonal Antibody is a Rabbit antibody targeting ROR gamma T. Anti-ROR gamma T Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM. |
疾病造模方案 | |
别名 | TOR, RZR-GAMMA, RZRG, RORγ, RORy, RORgT, RORG, ROR γ, ROR y, ROR gamma T [Mus musculus], ROR gamma, Retinoid-related orphan receptor-gamma, RAR-related orphan receptor C, Nuclear receptor subfamily 1 group F member 3, Nuclear receptor RZR-gamma, nuclear receptor ROR-gamma isoform 2, Nuclear receptor ROR-gamma, NR1F3, IMD42 |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit) |
验证活性 | 1. Sample: Lane1: Mouse Muscle Lysates Lane2: Rat Muscle Lysates Primary: Anti-ROR Gamma T at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 57 kDa Observed band size: 50 kDa 2. Sample: Muscle (mouse) Lysate at 40 μg Kidney (mouse) Lysate at 40 μg Primary: Anti-ROR gamma T (TMAB-01630) at 1/300 dilution Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution Predicted band size: 54 kDa Observed band size: 54 kDa 3. Sample: Lane1: Mouse Muscle Lysates Lane2: Rat Muscle Lysates Primary: Anti-ROR Gamma (TMAB-01630) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 57 kDa Observed band size: 50 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100; IF: 1:100-500; FCM: 1ug/test |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Nucleus (Probable). |
组织特异性 | Isoform 1: widely expressed in many tissues, including liver and adipose, and highly expressed in skeletal muscle. Isoform 2: Primarily expressed in immature thymocytes. |
构建方式 | Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
浓度 | 1 mg/mL |
研究背景 | The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
免疫原 | KLH conjugated synthetic peptide: mouse ROR gamma T |
抗原种属 | Mouse |
基因名称 | RORC |
基因ID | |
蛋白名称 | Nuclear receptor ROR-gamma |
Uniprot ID | |
研究领域 | Corticoid,Transcription Factors,Hormones |
功能 | Possible nuclear receptor for hydroxycholesterols, the binding of which strongly promotes coactivators recruitment. Essential for thymopoiesis and the development of several secondary lymphoid tissues, including lymph nodes. Involved in lineage specification of uncommitted CD4(+) T helper cells into Th17 cells. Regulate the expression of several components of the circadian clock. |
分子量 | Theoretical: 54 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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