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Anti-ROR gamma T Polyclonal Antibody

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Anti-ROR gamma T Polyclonal Antibody
产品编号 TMAB-01630
别名 TOR, RZR-GAMMA, RZRG, RORγ, RORy, RORgT, RORG, ROR γ, ROR y, ROR gamma T [Mus musculus], ROR gamma, Retinoid-related orphan receptor-gamma, RAR-related orphan receptor C, Nuclear receptor subfamily 1 group F member 3, Nuclear receptor RZR-gamma, nuclear receptor ROR-gamma isoform 2, Nuclear receptor ROR-gamma, NR1F3, IMD42

Anti-ROR gamma T Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ROR gamma T。Anti-ROR gamma T Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

Anti-ROR gamma T Polyclonal Antibody

Anti-ROR gamma T Polyclonal Antibody

Rating icon 还可以
Anti-ROR gamma T Polyclonal Antibody
产品编号 TMAB-01630 别名 TOR, RZR-GAMMA, RZRG, RORγ, RORy, RORgT, RORG, ROR γ, ROR y, ROR gamma T [Mus musculus], ROR gamma, Retinoid-related orphan receptor-gamma, RAR-related orphan receptor C, Nuclear receptor subfamily 1 group F member 3, Nuclear receptor RZR-gamma, nuclear receptor ROR-gamma isoform 2, Nuclear receptor ROR-gamma, NR1F3, IMD42

Anti-ROR gamma T Polyclonal Antibody 是一种 Rabbit 抗体,靶向 ROR gamma T。Anti-ROR gamma T Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-ROR gamma T Polyclonal Antibody is a Rabbit antibody targeting ROR gamma T. Anti-ROR gamma T Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF,FCM.
疾病造模方案
别名TOR, RZR-GAMMA, RZRG, RORγ, RORy, RORgT, RORG, ROR γ, ROR y, ROR gamma T [Mus musculus], ROR gamma, Retinoid-related orphan receptor-gamma, RAR-related orphan receptor C, Nuclear receptor subfamily 1 group F member 3, Nuclear receptor RZR-gamma, nuclear receptor ROR-gamma isoform 2, Nuclear receptor ROR-gamma, NR1F3, IMD42
Ig Type
IgG
交叉反应
Human,Mouse,Rat (predicted:Chicken,Dog,Pig,Cow,Horse,Rabbit)
验证活性
1. Sample:
Lane1: Mouse Muscle Lysates
Lane2: Rat Muscle Lysates
Primary: Anti-ROR Gamma T at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 57 kDa
Observed band size: 50 kDa
2. Sample:
Muscle (mouse) Lysate at 40 μg
Kidney (mouse) Lysate at 40 μg
Primary: Anti-ROR gamma T (TMAB-01630) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-RabbitIgG at 1/20000 dilution
Predicted band size: 54 kDa
Observed band size: 54 kDa
3. Sample:
Lane1: Mouse Muscle Lysates
Lane2: Rat Muscle Lysates
Primary: Anti-ROR Gamma (TMAB-01630) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 57 kDa
Observed band size: 50 kDa
应用
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100; IF: 1:100-500; FCM: 1ug/test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus (Probable).
组织特异性Isoform 1: widely expressed in many tissues, including liver and adipose, and highly expressed in skeletal muscle. Isoform 2: Primarily expressed in immature thymocytes.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known; however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: mouse ROR gamma T
抗原种属
Mouse
基因名称
RORC
基因ID
蛋白名称
Nuclear receptor ROR-gamma
Uniprot ID
研究领域
Corticoid,Transcription Factors,Hormones
功能
Possible nuclear receptor for hydroxycholesterols, the binding of which strongly promotes coactivators recruitment. Essential for thymopoiesis and the development of several secondary lymphoid tissues, including lymph nodes. Involved in lineage specification of uncommitted CD4(+) T helper cells into Th17 cells. Regulate the expression of several components of the circadian clock.
化学信息
分子量Theoretical: 54 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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