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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-FGD5 Polyclonal Antibody

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货号 TMAB-05978

Anti-FGD5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FGD5。Anti-FGD5 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-FGD5 Polyclonal Antibody

Anti-FGD5 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-05978

Anti-FGD5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 FGD5。Anti-FGD5 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-FGD5 Polyclonal Antibody is a Rabbit antibody targeting FGD5. Anti-FGD5 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Dog)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton. Cell projection, ruffle membrane. Endoplasmic reticulum. Golgi apparatus. Early endosome. Note=In peripheral membrane ruffles, colocolizes with F-actin. In confluent HUVECs, detected at cell-cell-contact sites where it colocalizes with vascular endothelial cadherin/CDH5.
组织特异性Expressed in endothelial cells (at protein level).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景FGD5 is a 1,462 amino acid cytosolic protein that contains a DH domain, a FYVE-type zinc finger and two PH domains. FGD family members encode guanine nucleotide exchange factors that specifically activate the Rho GTPase Cdc42. All FGD proteins contain equivalent signaling domains and a conserved structural organization, which strongly suggests that these signaling domains form a canonical core structure for members of the FGD family of RhoGEF proteins. These proteins also control essential signals required during embryonic development.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FGD5
抗原种属
Human
基因名称
FGD5
基因ID
152273
蛋白名称
FYVE, RhoGEF and PH domain-containing protein 5
Uniprot ID
Q6ZNL6
功能
FGD5 may activate CDC42, a member of the Ras like family of Rho and Rac proteins, by exchanging bound GDP for free GTP. It may also play a role in regulating the actin cytoskeleton and cell shape. FGD5 contains one DH (DBL-homology) domain one FYVE type zinc finger and two PH domains. There are two isoforms.
化学信息
分子量Theoretical: 160 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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