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Clusterin Protein, Mouse, Recombinant (His) V2

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产品编号 TMPY-01694U

Clusterin Protein, Mouse, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q06890.

Clusterin Protein, Mouse, Recombinant (His) V2

一键复制产品信息

产品编号 TMPY-01694U

Clusterin Protein, Mouse, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q06890.

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产品信息

生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it.
产品描述	Clusterin Protein, Mouse, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is Q06890.
种属	Mouse
表达系统	HEK293 Cells
标签	C-His
蛋白编号	Q06890
蛋白构建	Glu22-Glu448
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	50.4 kDa (Predicted); 35-40 kDa and 43-50 kDa (due to autocatalytic cleavage)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
研究背景	Clusterin (CLU) is a stress-activated, ATP-independent molecular chaperone, normally secreted from cells, that is up-regulated in Alzheimer disease and in many cancers. It plays important roles in protein homeostasis/proteostasis, inhibition of cell death pathways, and modulation of pro-survival signalling and transcriptional networks. Changes in the CLU gene locus are highly associated with Alzheimer disease, and many therapy-resistant cancers over-express CLU.