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别名 Serine sulfhydrase, Cystathionine beta-synthase, CBS, Beta-thionase
Anti-CBS Antibody (7N696) 是一种 Rabbit 抗体,靶向 CBS。Anti-CBS Antibody (7N696) 可用于 ICC,WB。
Anti-CBS Antibody (7N696) 是一种 Rabbit 抗体,靶向 CBS。Anti-CBS Antibody (7N696) 可用于 ICC,WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,490 | 5日内发货 |
| 产品描述 | Anti-CBS Antibody (7N696) is a Rabbit antibody targeting CBS. Anti-CBS Antibody (7N696) can be used in ICC,WB. |
| 别名 | Serine sulfhydrase, Cystathionine beta-synthase, CBS, Beta-thionase |
| Ig Type | IgG |
| 克隆号 | 7N696 |
| 交叉反应 | Human |
| 验证活性 | 1. Western blot analysis of CBS on different lysates using anti-CBS antibody at 1/1,000 dilution.Positive control: Lane 1: 293, Lane 2: 293, Lane 3: human liver tissue. 2. ICC staining CBS in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. ![]() ![]() |
| 应用 | ICCWB |
| 推荐剂量 | WB: 1:500-2000; ICC: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Strongly expressed in human liver and pancreas, with weaker expression in heart and brain, the cytoplasmic protein cystathionine b-synthase (CBS) operates in the first step of homocysteine transulfuration. CBS, which belongs to the cysteine synthase/cystathionine b-synthase family of proteins, catalyzes the formation of cystathionine from the thrombogenic amino acid homocysteine using pyridoxal phosphate cofactor. Allosteric activation by adenosyl-methionine regulates CBS activity. Deficiencies in CBS are assoc-iated with homocystinuria, a recessively inherited error in sulfur amino acid metabolism that affects many organs and tissues. Symptoms of homocytinuria include arteriosclerosis, thrombosis, dislocated optic lenses, mental retard-ation and skeletal abnormalities. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: human CBS aa 400-550 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 61 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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