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Anti-CBS Antibody (7N696) 是一种 Rabbit 抗体,靶向 CBS。Anti-CBS Antibody (7N696) 可用于 WB,ICC。
Anti-CBS Antibody (7N696) 是一种 Rabbit 抗体,靶向 CBS。Anti-CBS Antibody (7N696) 可用于 WB,ICC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,490 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-CBS Antibody (7N696) is a Rabbit antibody targeting CBS. Anti-CBS Antibody (7N696) can be used in WB,ICC. |
别名 | Serine sulfhydrase, Cystathionine beta-synthase, CBS, Beta-thionase |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of CBS on different lysates using anti-CBS antibody at 1/1,000 dilution.Positive control: Lane 1: 293, Lane 2: 293, Lane 3: human liver tissue. 2. ICC staining CBS in 293T cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
应用 | |
推荐剂量 | WB: 1:500-2000; ICC: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Strongly expressed in human liver and pancreas, with weaker expression in heart and brain, the cytoplasmic protein cystathionine b-synthase (CBS) operates in the first step of homocysteine transulfuration. CBS, which belongs to the cysteine synthase/cystathionine b-synthase family of proteins, catalyzes the formation of cystathionine from the thrombogenic amino acid homocysteine using pyridoxal phosphate cofactor. Allosteric activation by adenosyl-methionine regulates CBS activity. Deficiencies in CBS are assoc-iated with homocystinuria, a recessively inherited error in sulfur amino acid metabolism that affects many organs and tissues. Symptoms of homocytinuria include arteriosclerosis, thrombosis, dislocated optic lenses, mental retard-ation and skeletal abnormalities. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein: human CBS aa 400-550 |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 61 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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