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Anti-AKR1B10 Polyclonal Antibody

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货号 TMAB-02406

Anti-AKR1B10 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 AKR1B10。Anti-AKR1B10 Polyclonal Antibody 可用于 WB。

Anti-AKR1B10 Polyclonal Antibody

Anti-AKR1B10 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02406

Anti-AKR1B10 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 AKR1B10。Anti-AKR1B10 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-AKR1B10 Polyclonal Antibody is a Rabbit antibody targeting AKR1B10. Anti-AKR1B10 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Lysosome. Secreted. Note=Secreted through a lysosome-mediated non-classical pathway.
组织特异性Found in many tissues. Highly expressed in small intestine, colon and adrenal gland.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景AKR1B10 is also known as aldose reductase-like-1 (ARL-1), small intestine reductase (SI reductase) or aldose reductase-related protein (ARP or hARP). AKR1B10 is found in many tissues but is predominantly expressed in small intestine, colon and adrenal gland. AKR1B10 is an efficient reductase for aliphatic and aromatic aldehydes. It plays a role in steroid metabolism as well as detoxification of aldehydes in digested food, and may be involved in the retinal-retinoic acid signaling pathway. AKR1B10 is prominently overexpressed in non-small cell lung carcinoma and adenocarcinoma. Cigarette smoking is an independent variable responsible for this overexpression. AKR1B10 may play a role regulating cell proliferation and cellular response to carbonyl stress.
抗原信息
免疫原
KLH conjugated synthetic peptide: human AKR1B10
抗原种属
Human
基因名称
AKR1B10
基因ID
蛋白名称
Aldo-keto reductase family 1 member B10
Uniprot ID
功能
Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs.
化学信息
分子量Theoretical: 35 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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