购物车
全部删除
您的购物车当前为空
Anti-AKR1B10 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 AKR1B10。Anti-AKR1B10 Polyclonal Antibody 可用于 WB。
Anti-AKR1B10 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 AKR1B10。Anti-AKR1B10 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-AKR1B10 Polyclonal Antibody is a Rabbit antibody targeting AKR1B10. Anti-AKR1B10 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat,Rabbit) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Lysosome. Secreted. Note=Secreted through a lysosome-mediated non-classical pathway. |
| 组织特异性 | Found in many tissues. Highly expressed in small intestine, colon and adrenal gland. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | AKR1B10 is also known as aldose reductase-like-1 (ARL-1), small intestine reductase (SI reductase) or aldose reductase-related protein (ARP or hARP). AKR1B10 is found in many tissues but is predominantly expressed in small intestine, colon and adrenal gland. AKR1B10 is an efficient reductase for aliphatic and aromatic aldehydes. It plays a role in steroid metabolism as well as detoxification of aldehydes in digested food, and may be involved in the retinal-retinoic acid signaling pathway. AKR1B10 is prominently overexpressed in non-small cell lung carcinoma and adenocarcinoma. Cigarette smoking is an independent variable responsible for this overexpression. AKR1B10 may play a role regulating cell proliferation and cellular response to carbonyl stress. |
| 免疫原 | KLH conjugated synthetic peptide: human AKR1B10 |
| 抗原种属 | Human |
| 基因名称 | AKR1B10 |
| 基因ID | |
| 蛋白名称 | Aldo-keto reductase family 1 member B10 |
| Uniprot ID | |
| 功能 | Acts as all-trans-retinaldehyde reductase. Can efficiently reduce aliphatic and aromatic aldehydes, and is less active on hexoses (in vitro). May be responsible for detoxification of reactive aldehydes in the digested food before the nutrients are passed on to other organs. |
| 分子量 | Theoretical: 35 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |