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Anti-Serpin B3 Antibody (2B774)
还可以产品编号 TMAY-02539
Anti-Serpin B3 Antibody (2B774) 是一种 Mouse 抗体，靶向 Serpin B3。Anti-Serpin B3 Antibody (2B774) 可用于 WB,ELISA。
Anti-Serpin B3 Antibody (2B774)
Anti-Serpin B3 Antibody (2B774)
还可以产品编号 TMAY-02539
Anti-Serpin B3 Antibody (2B774) 是一种 Mouse 抗体，靶向 Serpin B3。Anti-Serpin B3 Antibody (2B774) 可用于 WB,ELISA。
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偶联与修饰
抗原信息
| 产品描述 | Anti-Serpin B3 Antibody (2B774) is a Mouse antibody targeting Serpin B3. Anti-Serpin B3 Antibody (2B774) can be used in WB,ELISA. |
| Ig Type | Monoclonal Mouse IgG2a |
| 克隆号 | 2B774 |
| 交叉反应 | Human |
| 验证活性 | Anti-SerpinB3 mouse monoclonal antibody at 1:500 dilution. -Lane A: A431 Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Mouse IgG (H+L)/HRP at 1/10000 dilution. -Developed using the ECL technique. -Performed under reducing conditions. -Predicted band size:45 kDa. -Observed band size:45 kDa(We are unsure as to the identity of these extra bands.) |
| 应用 | WB,ELISA |
| 推荐剂量 | WB: 1:500-1:2000; ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SerpinB3 (rh SerpinB3; TMPY-02712; AAB20405.1; Asn2-Pro390). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | SERPINB3, also known as SCCA-1, belongs to the serpin family. Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. SERPINB3 is expressed in some hepatocellular carcinoma (at protein level). Its expression is closely related to cellular differentiation in both normal and malignant squamous cells. It seems to also be secreted in plasma by cancerous cells but at a low level. SERPINB3 significantly attenuates apoptosis by contrasting cytochrome c release from the mitochondria and by antichemotactic effect for NK cells. It may act as a protease inhibitor to modulate the host immune response against tumor cells and may be involved in the malignant behavior of squamous cell carcinoma cells. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human SerpinB3 Protein (TMPY-02712) |
| 抗原种属 | Human |
| 研究领域 | Serine Proteases and Regulators |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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