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Anti-Phospho-IRF3 (Ser386) Antibody (1U230) 是一种 Rabbit 抗体,靶向 Phospho-IRF3 (Ser386)。Anti-Phospho-IRF3 (Ser386) Antibody (1U230) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。
Anti-Phospho-IRF3 (Ser386) Antibody (1U230) 是一种 Rabbit 抗体,靶向 Phospho-IRF3 (Ser386)。Anti-Phospho-IRF3 (Ser386) Antibody (1U230) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 μL | ¥ 785 | 5日内发货 | |
50 μL | ¥ 1,390 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-Phospho-IRF3 (Ser386) Antibody (1U230) is a Rabbit antibody targeting Phospho-IRF3 (Ser386). Anti-Phospho-IRF3 (Ser386) Antibody (1U230) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF. |
Ig Type | IgG |
克隆号 | 1U230 |
交叉反应 | Human (predicted:Mouse,Rat,Dog,Pig,Cow,Rabbit,Sheep) |
验证活性 | MCF7 cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Antibody incubation with (Phospho-IRF3 (S386)) monoclonal Antibody, Unconjugated (TMAB-01435) 1:50, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue) was used to stain the cell nucleus. |
应用 | |
推荐剂量 | WB: 1:500-1000; IHC-P: 1:100-500; IHC-Fr: 1:50-200; ICC/IF: 1:50; IF: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
亚细胞定位 | Cytoplasm. Nucleus. Note=Shuttles between cytoplasmic and nuclear compartments, with export being the prevailing effect. When activated, IRF3 interaction with CREBBP prevents its export to the cytoplasm. |
构建方式 | Recombinant Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]. |
免疫原 | KLH conjugated synthesised phosphopeptide: human IRF3 around the phosphorylation site of Ser386 |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | SARS Coronavirus,TLR Signaling,Interferons,Other factors |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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