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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-GRK3 Polyclonal Antibody

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货号 TMAB-06781

Anti-GRK3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GRK3。Anti-GRK3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-GRK3 Polyclonal Antibody

Anti-GRK3 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06781

Anti-GRK3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GRK3。Anti-GRK3 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-GRK3 Polyclonal Antibody is a Rabbit antibody targeting GRK3. Anti-GRK3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Chicken,Dog,Cow,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
浓度1mg/ml
研究背景Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist. This phenomenon, referred to as agonist-mediated desensitization, involves phosphorylation of the receptor by two classes of enzymes. The first class is comprised of the second messenger-regulated kinases, such as c-AMP dependent protein kinase A and protein kinase C. The second class includes the G protein-coupled receptor kinases (GRKs). At least seven members of the GRK family have been identified. These include rhodopsin kinase (GRK 1), two forms of Beta-adrenergic receptor kinase: GRK 2 (Beta ARK, Beta ARK1) and GRK 3 (Beta ARK2), IT-11 (GRK 4), GRK 5, GRK 6 and GRK 7. Phosphorylation of receptors by GRKs appears to be strictly dependent on the receptor being in its agonist-activated state.
抗原信息
免疫原
KLH conjugated synthetic peptide: human GRK3
抗原种属
Human
基因名称
GRK3
基因ID
157
蛋白名称
beta-adrenergic receptor kinase 2
Uniprot ID
P35626
功能
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.
化学信息
分子量Theoretical: 80 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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