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Anti-IL-13RA1 Antibody (4X475) 是一种 Mouse 抗体,靶向 IL-13RA1。Anti-IL-13RA1 Antibody (4X475) 可用于 ELISA。
Anti-IL-13RA1 Antibody (4X475) 是一种 Mouse 抗体,靶向 IL-13RA1。Anti-IL-13RA1 Antibody (4X475) 可用于 ELISA。
产品描述 | Anti-IL-13RA1 Antibody (4X475) is a Mouse antibody targeting IL-13RA1. Anti-IL-13RA1 Antibody (4X475) can be used in ELISA. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 4X475 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:1000-1:2000 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL13RA1 extracellular domain (rh IL13RA1; TMPY-01258; NP_001551.1; Met 1-Thr 343). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography . |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Interleukin 13 receptor, alpha 1, also known as IL13RA1/IL-13RA1 and CD213A1 (cluster of differentiation 213A1), is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. IL13RA1/IL-13RA1 serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2 and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3, and STAT6 induced by IL13 and IL4. IL13RA1/IL-13RA1 binds with low affinity to interleukin-13 (IL13). This subunit together with IL4RA can form a functional receptor for IL13. IL13RA1/IL-13RA1 also serves as an alternate accessory protein to the common cytokine receptor gamma chain for interleukin-4 (IL4) signaling, but cannot replace the function of IL2RG in allowing enhanced interleukin-2 (IL2) binding activity. |
偶联 | Unconjugated |
免疫原 | Recombinant Human IL13RA1 protein (TMPY-01258) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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