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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-METTL3 Polyclonal Antibody

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货号 TMAB-01127

别名 N(6)-adenosine-methyltransferase catalytic subunit METTL3, N(6)-adenosine-methyltransferase 70 kDa subunit (MT-A70), MTA70, METTL3, Methyltransferase-like protein 3 (hMETTL3)

Anti-METTL3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 METTL3。Anti-METTL3 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

Anti-METTL3 Polyclonal Antibody

Anti-METTL3 Polyclonal Antibody

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货号 TMAB-01127 别名 N(6)-adenosine-methyltransferase catalytic subunit METTL3, N(6)-adenosine-methyltransferase 70 kDa subunit (MT-A70), MTA70, METTL3, Methyltransferase-like protein 3 (hMETTL3)

Anti-METTL3 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 METTL3。Anti-METTL3 Polyclonal Antibody 可用于 IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-METTL3 Polyclonal Antibody is a Rabbit antibody targeting METTL3. Anti-METTL3 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
别名N(6)-adenosine-methyltransferase catalytic subunit METTL3, N(6)-adenosine-methyltransferase 70 kDa subunit (MT-A70), MTA70, METTL3, Methyltransferase-like protein 3 (hMETTL3)
Ig Type
IgG
反应种属
Rat (predicted:Human,Mouse,Pig,Cow,Rabbit,Sheep)
验证活性
1. Paraformaldehyde-fixed, paraffin embedded (rat testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (METTL3) Polyclonal Antibody, Unconjugated (TMAB-01127) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded (rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (METTL3) Polyclonal Antibody, Unconjugated (TMAB-01127) at 1:200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructionsand DAB staining.
verifiedActivityverifiedActivity
应用IFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus speckle. Colocalizes with speckles in interphase nuclei. Suggesting that it may be associated with nuclear pre-mRNA splicing components.
组织特异性Widely expressed at low level. Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon and peripheral blood leukocytes.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human METTL3
抗原种属
Human
基因名称
METTL3
基因ID
56339
蛋白名称
N6-adenosine-methyltransferase catalytic subunit
Uniprot ID
Q86U44
研究领域
DNA / Nucleotides,RNA Processing
功能
N6-methyltransferase that methylates adenosine residues of some mRNAs. N6-methyladenosine (m6A), which is present at internal sites of some mRNAs, may play a role in the efficiency of mRNA splicing, transport or translation.
化学信息
分子量Theoretical: 64 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

计算器

  • 稀释 计算器

关键词

MTA 70METTL 3hMETTL3hMETTL 3
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