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Anti-CD40 Monoclonal Antibody (5E622) 是一种 Mouse 抗体,靶向 CD40。Anti-CD40 Monoclonal Antibody (5E622) 可用于 IF。
别名 TNFRSF5, p50, CDW40, Bp50
Anti-CD40 Monoclonal Antibody (5E622) 是一种 Mouse 抗体,靶向 CD40。Anti-CD40 Monoclonal Antibody (5E622) 可用于 IF。

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| 产品描述 | Anti-CD40 Monoclonal Antibody (5E622) is a Mouse antibody targeting CD40. Anti-CD40 Monoclonal Antibody (5E622) can be used in IF. |
| 别名 | TNFRSF5, p50, CDW40, Bp50 |
| Ig Type | IgG1 |
| 克隆号 | 5E622 |
| 反应种属 | Human |
| 应用 | IF |
| 推荐剂量 | IF: 1/200-1/1000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | Hybridoma Monoclonal Antibody |
| 纯化方式 | Purified by protein A or protein G |
| 性状 | Liquid |
| 缓冲液 | Ascitic fluid containing 0.03% sodium azide |
| 浓度 | 1 mg/ml |
| 研究背景 | CD40 molecule, TNF receptor superfamily member 5. It is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| 偶联 | Unconjugated |
| 免疫原 | Purified recombinant fragment of CD40 expressed in E. Coli. |
| 抗原种属 | Human |
| 基因名称 | CD40 |
| 基因ID | |
| 蛋白名称 | Tumor necrosis factor receptor superfamily member 5 |
| Uniprot ID |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |