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Anti-IMPDH1 Polyclonal Antibody

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货号 TMAB-07691

Anti-IMPDH1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IMPDH1。Anti-IMPDH1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

Anti-IMPDH1 Polyclonal Antibody

Anti-IMPDH1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-07691

Anti-IMPDH1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IMPDH1。Anti-IMPDH1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-IMPDH1 Polyclonal Antibody is a Rabbit antibody targeting IMPDH1. Anti-IMPDH1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Mouse,Rat (predicted:Dog,Pig,Cow,Rabbit,GuineaPig)
应用WBIHC-PIHC-FrIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
组织特异性IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].
抗原信息
免疫原
KLH conjugated synthetic peptide: human IMPDH1
抗原种属
Human
基因名称
IMPDH1
基因ID
蛋白名称
Inosine-5'-monophosphate dehydrogenase 1
Uniprot ID
功能
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
化学信息
分子量Theoretical: 55 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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