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Anti-IMPDH1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IMPDH1。Anti-IMPDH1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,FCM。
Anti-IMPDH1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IMPDH1。Anti-IMPDH1 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,165 | 5日内发货 | |
| 100 μL | ¥ 1,975 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-IMPDH1 Polyclonal Antibody is a Rabbit antibody targeting IMPDH1. Anti-IMPDH1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| 反应种属 | Human,Mouse,Rat (predicted:Dog,Pig,Cow,Rabbit,GuineaPig) |
| 应用 | WBIHC-PIHC-FrIFFCM |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Nucleus. |
| 组织特异性 | IMP type I is the main species in normal leukocytes and type II predominates over type I in the tumor. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]. |
| 免疫原 | KLH conjugated synthetic peptide: human IMPDH1 |
| 抗原种属 | Human |
| 基因名称 | IMPDH1 |
| 基因ID | |
| 蛋白名称 | Inosine-5'-monophosphate dehydrogenase 1 |
| Uniprot ID | |
| 功能 | Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors. |
| 分子量 | Theoretical: 55 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |