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Anti-FAIM3 Polyclonal Antibody 2

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货号 TMAB-05806

Anti-FAIM3 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 FAIM3。Anti-FAIM3 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-FAIM3 Polyclonal Antibody 2

Anti-FAIM3 Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-05806

Anti-FAIM3 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 FAIM3。Anti-FAIM3 Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
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100 μL
¥ 1,960
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200 μL
¥ 2,795
5日内发货
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产品介绍

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产品描述
Anti-FAIM3 Polyclonal Antibody 2 is a Rabbit antibody targeting FAIM3. Anti-FAIM3 Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform 1: Membrane; Single-pass membrane protein. Isoform 3: Secreted. Note=Detected in the serum.
组织特异性Expressed in lymph nodes, peripheral blood leukocytes, lung, thymus and kidneys. Very weak expression detected in spleen, liver, heart, and salivary gland. Expressed in lymphoid cell lines such as Jurkat, CEM-T4, MOLT-4, HB11;19 and Reh. No expression detected in nonhematopoietic cell lines including Hep-G2, HEK293 and HeLa. Detected at high levels in chronic lymphocytic leukemia cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human FAIM3
抗原种属
Human
基因名称
FCMR
基因ID
9214
蛋白名称
Fas apoptotic inhibitory molecule 3
Uniprot ID
O60667
功能
May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
化学信息
分子量Theoretical: 41 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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