购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部生物活性储存和溶解信息计算器

Anti-Phospho-Histone H3 (Ser28) Antibody (5K486)

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-10801

种类：Recombinant Mouse Monoclonal
应用：WB
交叉反应：Human (predicted:Mouse,Rat)

Anti-Phospho-Histone H3 (Ser28) Antibody (5K486)

Anti-Phospho-Histone H3 (Ser28) Antibody (5K486)

一键复制产品信息
Rating icon 还可以
产品编号 TMAB-10801

种类：Recombinant Mouse Monoclonal
应用：WB
交叉反应：Human (predicted:Mouse,Rat)

TargetMol
产品信息正在更新中，如果您想购买，请点击大包装&定制按钮.
大包装 & 定制
实验操作小课堂
常见问题解答
查看更多
联系我们获取更多批次信息
资源下载
产品操作手册

产品介绍

生物活性
产品描述
Anti-Phospho-Histone H3 (Ser28) Antibody (5K486) is a Mouse antibody targeting Phospho-Histone H3 (Ser28). Anti-Phospho-Histone H3 (Ser28) Antibody (5K486) can be used in WB.
Ig Type
IgG2b/Kappa
克隆号
5K486
交叉反应
Human (predicted:Mouse,Rat)
应用WB
推荐剂量
WB: 1:500-1000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Nucleus. Chromosome. Note=Localizes to both the large, transcriptionally active, somatic macronucleus (MAC) and the small, transcriptionally inert, germ line micronucleus (MIC).
组织特异性Expressed in testicular cells.Expressed during S phase, then expression strongly decreases as cell division slows down during the process of differentiation.
构建方式Recombinant Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Modulation of the chromatin structure plays an important role in the regulation of transcription in eukaryotes. The nucleosome, made up of four core histone proteins (H2A, H2B, H3 and H4), is the primary building block of chromatin. The N-terminal tail of core histones undergoes different posttranslational modifications including acetylation, phosphorylation and methylation. These modifications occur in response to cell signal stimuli and have a direct effect on gene expression. In most species, the histone H2B is primarily acetylated at lysines 5, 12, 15 and 20. Histone H3 is primarily acetylated at lysines 9, 14, 18 and 23. Acetylation at lysine 9 appears to have a dominant role in histone deposition and chromatin assembly in some organisms. Phosphorylation at Ser10 of histone H3 is tightly correlated with chromosome condensation during both mitosis and meiosis.
抗原信息
基因名称
H3C1
基因ID
8350
蛋白名称
Histone H3.1
功能
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H3 is deposited into chromatin exclusively through a DNA replication-coupled pathway that can be associated with either DNA duplication or DNA repair synthesis during meiotic homologous recombination.
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

评论列表

4个月前
5.0
Rating icon 很棒

评论内容

233
Related Tags: buy Anti-Phospho-Histone H3 (Ser28) Antibody (5K486) | purchase Anti-Phospho-Histone H3 (Ser28) Antibody (5K486) | Anti-Phospho-Histone H3 (Ser28) Antibody (5K486) cost | order Anti-Phospho-Histone H3 (Ser28) Antibody (5K486)