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Anti-GAPDH Antibody (1K747)
还可以产品编号 TMAH-00473
别名 HEL-S-162eP, glyceraldehyde-3-phosphate dehydrogenase, GAPD, G3PD
Anti-GAPDH Antibody (1K747) 是一种抗体，靶向 GAPDH。Anti-GAPDH Antibody (1K747) 可用于 ELISA, WB。
Anti-GAPDH Antibody (1K747)
Anti-GAPDH Antibody (1K747)
还可以产品编号 TMAH-00473 别名 HEL-S-162eP, glyceraldehyde-3-phosphate dehydrogenase, GAPD, G3PD
Anti-GAPDH Antibody (1K747) 是一种抗体，靶向 GAPDH。Anti-GAPDH Antibody (1K747) 可用于 ELISA, WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,190 | 5日内发货 |
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产品介绍
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抗原信息
| 产品描述 | Anti-GAPDH Antibody (1K747) is an antibody targeting GAPDH. Anti-GAPDH Antibody (1K747) can be used in ELISA, WB. |
| 别名 | HEL-S-162eP, glyceraldehyde-3-phosphate dehydrogenase, GAPD, G3PD |
| Ig Type | Rabbit IgG |
| 克隆号 | 1K747 |
| 交叉反应 | Human, Mouse |
| 验证活性 | Western Blot -Positive WB detected in U87 whole cell lysate, Mouse brain tissue -All lanes GAPDH antibody at 0.31μg/ml -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 36 KDa -Observed band size: 36 KDa |
| 应用 | ELISA, WB |
| 推荐剂量 | WB:1:3000-1:10000. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cytoplasm, cytosol. Nucleus. Cytoplasm, perinuclear region. Membrane. Cytoplasm, cytoskeleton. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation. Also plays a role in innate immunity by promoting TNF-induced NF-kappa-B activation and type I interferon production, via interaction with TRAF2 and TRAF3, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide |
| 抗原种属 | Human |
| 基因ID | 2597 |
| Uniprot ID | |
| 研究领域 | Neuroscience |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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