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Anti-PHGDH Antibody (9Z346)
还可以产品编号 TMAY-02517
别名 SERA, phosphoglycerate dehydrogenase, PHGDHD, PGDH, PGD, PGAD, PDG, NLS1, NLS, HEL-S-113, 3-PGDH, 3PGDH
Anti-PHGDH Antibody (9Z346) 是一种 Mouse 抗体，靶向 PHGDH。Anti-PHGDH Antibody (9Z346) 可用于 ELISA。
Anti-PHGDH Antibody (9Z346)
Anti-PHGDH Antibody (9Z346)
还可以产品编号 TMAY-02517 别名 SERA, phosphoglycerate dehydrogenase, PHGDHD, PGDH, PGD, PGAD, PDG, NLS1, NLS, HEL-S-113, 3-PGDH, 3PGDH
Anti-PHGDH Antibody (9Z346) 是一种 Mouse 抗体，靶向 PHGDH。Anti-PHGDH Antibody (9Z346) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 1,689 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-PHGDH Antibody (9Z346) is a Mouse antibody targeting PHGDH. Anti-PHGDH Antibody (9Z346) can be used in ELISA. |
| 别名 | SERA, phosphoglycerate dehydrogenase, PHGDHD, PGDH, PGD, PGAD, PDG, NLS1, NLS, HEL-S-113, 3-PGDH, 3PGDH |
| Ig Type | Monoclonal Mouse IgG2b |
| 克隆号 | 9Z346 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PGDH / PHGDH (rh PGDH / PHGDH; TMPY-02801; O43175; Met1-Phe533). The IgG fraction of the cell culture supernatant was purified by Protein A affinity. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the substrate binding and the catalytic reaction, and thus to be targets for site-directed mutagenesis. A number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to be specific for the D-isomer of their substrate have been shown to be functionally and structurally related. PHGDH catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor. Overexpression of PHGDH may cause certain breast cancers. Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency which is characterized by congenital microcephaly, psychomotor retardation, and seizures. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human PGDH / PHGDH protein (TMPY-02801) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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