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顶部生物活性储存和溶解信息计算器

Anti-Phospho-YAP1 (Ser127) Antibody (5V148)

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Anti-Phospho-YAP1 (Ser127) Antibody (5V148)
产品编号 TMAC-03284
别名 YAP1 (p-Ser127), YAP1 (p-S127), p-YAP1 (Ser127), p-YAP1 (S127), Phospho-YAP1 (S127)

Anti-Phospho-YAP1 (S127) Antibody (5V148) 是一种 Rabbit 抗体，靶向 Phospho-YAP1 (S127)。Anti-Phospho-YAP1 (S127) Antibody (5V148) 可用于 WB,IHC。

Anti-Phospho-YAP1 (Ser127) Antibody (5V148)

Anti-Phospho-YAP1 (Ser127) Antibody (5V148)

Rating icon 还可以
Anti-Phospho-YAP1 (Ser127) Antibody (5V148)
产品编号 TMAC-03284 别名 YAP1 (p-Ser127), YAP1 (p-S127), p-YAP1 (Ser127), p-YAP1 (S127), Phospho-YAP1 (S127)

Anti-Phospho-YAP1 (S127) Antibody (5V148) 是一种 Rabbit 抗体，靶向 Phospho-YAP1 (S127)。Anti-Phospho-YAP1 (S127) Antibody (5V148) 可用于 WB,IHC。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-YAP1 (Ser127) Antibody (5V148) 是一种 Rabbit 抗体，靶向 Phospho-YAP1 (Ser127)。Anti-Phospho-YAP1 (Ser127) Antibody (5V148) 可用于 WB,IHC。
别名YAP1 (p-Ser127), YAP1 (p-S127), p-YAP1 (Ser127), p-YAP1 (S127), Phospho-YAP1 (S127)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-phospho-YAP1 (S127) antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-phospho-YAP1 (S127) antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-phospho-YAP1 (S127) antibody. Counter stained with hematoxylin.
应用
WB
IHC
推荐剂量
WB: 1:500-1000; IHC: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The Yes-associated protein, otherwise known as YAP, is a 14-3-3-binding molecule that was originally recognized by virtue of its ability to bind to the SH3 domain of Yes. The binding of YAP to 14-3-3 requires the phosphorylation of a homologous serine residue (Ser 112) in the YAP 14-3-3-binding motif. The highly conserved and ubiquitously expressed 14-3-3 proteins regulate differentiation, cell cycle progression and apoptosis by binding intracellular phosphoproteins involved in signal transduction. YAP may link events at the plasma membrane and cytoskeleton to inhibition of transcription in the nucleus in a manner regulated by 14-3-3 proteins. YAP shares homology with the WW domain of TAZ, transcriptional co-activator with PDZ-binding motif, which functions as a transcriptional co-activator by binding to the PPXY motif present in transcription factors. YAP is expressed at high levels in the lung, placenta, prostate, ovary and testis.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Human breast carcinoma tissue, human kidney tissue, mouse kidney tissue
抗原种属
human
Uniprot ID
P46937
化学信息
分子量Theoretical: 65 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

Yes-associated protein YAP65 homologYes-associated protein 1YAP65YAP1 (pSer127)YAP1 (pS127)YAP1 (phospho-Ser127)YAP1 (phospho-S127)YAP1YAP 65YAP 1Transcriptional coactivator YAP1pYAP1 (Ser127)pYAP1 (S127)Protein yorkie homolog

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