Name: AMIGO2 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPY-03387
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 683

6-8日内发货

10 μg

¥ 1,130

6-8日内发货

20 μg

¥ 1,930

5日内发货

50 μg

¥ 4,430

5日内发货

生物活性

产品描述	AMIGO2 Protein, Human, Recombinant (His) is expressed in HEK293 Cells. The accession number is Q86SJ2.
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it.
研究背景	Bromodomain and extraterminal domain inhibitors (BETi) represent promising therapeutic agents for metastatic melanoma, yet their mechanism of action remains unclear. Here we interrogated the transcriptional effects of BETi and identified AMIGO2, a transmembrane molecule, as a BET target gene essential for melanoma cell survival. AMIGO2 is upregulated in melanoma cells and tissues compared to human melanocytes and nevi, and AMIGO2 silencing in melanoma cells induces G1/S arrest followed by apoptosis.
种属	Human
表达系统	HEK293 Cells
标签	C-His
蛋白编号	Q86SJ2
蛋白构建	Val40-Thr398
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	DEGA, AMIGO-2, ALI1, adhesion molecule with Ig-like domain 2
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	42 kDa (Predicted); 60-70 kDa (Reducing conditions due to glycosylation)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

AMIGO2 Protein, Human, Recombinant (His)