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Anti-IGF1/IGF-I Antibody (4D934) 是一种 Rabbit 抗体,靶向 IGF1/IGF-I。Anti-IGF1/IGF-I Antibody (4D934) 可用于 ELISA。
Anti-IGF1/IGF-I Antibody (4D934) 是一种 Rabbit 抗体,靶向 IGF1/IGF-I。Anti-IGF1/IGF-I Antibody (4D934) 可用于 ELISA。
产品描述 | Anti-IGF1/IGF-I Antibody (4D934) is a Rabbit antibody targeting IGF1/IGF-I. Anti-IGF1/IGF-I Antibody (4D934) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 4D934 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human IGF1 (rh IGF1; TMPY-06982; P05019-1; Gly49-Ala118). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | IGF I, also known as Mechano Growth Factor, somatomedin-C, IGF-I, and IGF1, is a secreted protein that belongs to the insulin family. The insulin family, comprised of insulin, relaxin, insulin-like growth factors I and II ( IGF-I and IGF-II ), and possibly the beta-subunit of 7S nerve growth factor, represents a group of structurally related polypeptides whose biological functions have diverged. The IGFs, or somatomedins, constitute a class of polypeptides that have a key role in pre-adolescent mammalian growth. IGF-I expression is regulated by GH and mediates postnatal growth, while IGF-II appears to be induced by placental lactogen during prenatal development. IGF1 / IGF-I may be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. IGF1 / IGF-I stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also about enhancing glucose uptake. Defects in IGF1 / IGF-I are the cause of insulin-like growth factor I deficiency (IGF1 deficiency) which is an autosomal recessive disorder characterized by growth retardation, sensorineural deafness, and mental retardation. |
偶联 | Unconjugated |
免疫原 | Recombinant Human IGF1 protein (TMPY-06982) |
抗原种属 | Human |
研究领域 | Serine Proteases and Regulators |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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