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Anti-Phospho-GluR1 (S845) Antibody (3V414) 是一种 Rabbit 抗体,靶向 Phospho-GluR1 (S845)。Anti-Phospho-GluR1 (S845) Antibody (3V414) 可用于 WB,FCM。
Anti-Phospho-GluR1 (S845) Antibody (3V414) 是一种 Rabbit 抗体,靶向 Phospho-GluR1 (S845)。Anti-Phospho-GluR1 (S845) Antibody (3V414) 可用于 WB,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,490 | 5日内发货 |
产品描述 | Anti-Phospho-GluR1 (Ser845) Antibody (3V414) 是一种 Rabbit 抗体,靶向 Phospho-GluR1 (Ser845)。Anti-Phospho-GluR1 (Ser845) Antibody (3V414) 可用于 WB,FCM。 |
别名 | p-GluR1 (Ser845), p-GluR1 (S845), GluR1 (p-Ser845), GluR1 (p-S845) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Flow cytometric analysis of N2A cells with Phospho-GluR1 (S845) antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
应用 | |
推荐剂量 | WB: 1:500; FCM: 1:10-50 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human GluR1 around the phosphorylation site of Ser845 |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 102 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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