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DHQ

Name: DHQ
Brand: TargetMol
SKU: T20436
Price: 99 CNY
Availability: InStock
Rating: 5 (10 reviews)

Synonyms: 2,3-二羟基喹喔啉, 2,3-dihydroxy-quinoxalin

货号 T20436Cas号 15804-19-0 一键复制产品信息纯度: 99.89%

很棒

DHQ (2,3-dihydroxy-quinoxalin) 是单纯疱疹病毒胸苷激酶的 ATPase 活性诱导剂。

DHQ

一键复制产品信息

很棒

纯度: 99.89%

货号 T20436Cas号 15804-19-0

别名 2,3-二羟基喹喔啉, 2,3-dihydroxy-quinoxalin

DHQ (2,3-dihydroxy-quinoxalin) 是单纯疱疹病毒胸苷激酶的 ATPase 活性诱导剂。

规格	价格	库存
25 mg	¥ 161	现货
50 mg	¥ 265	现货
100 mg	¥ 419	现货
500 mg	¥ 1,120	现货
1 mL x 10 mM (in DMSO)	¥ 99	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

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纯度: 99.89%

颜色: 白色

性状: Solid

资源下载: COA HNMR LCMS产品操作手册

产品介绍

DHQ AI Summary

DHQ demonstrates a diverse range of bioactivities across several targets. It inhibits the binding of [3H]DCKA to the NMDA receptor in rat brain membranes with an IC50 value of 9800.0 nM and also inhibits [3H]glycine binding at the NMDA receptor glycine site, with various IC50 values reported (up to 39000.0 nM). It exhibits a binding affinity with a Kb value of 16500.0 nM towards the glycine site of the NMDA receptor and a significantly lower affinity towards other glutamate receptors. Additionally, DHQ shows inhibition of [3H]AMPA binding to AMPA receptors with low affinity (Ki > 100,000.0 nM), suggesting minimal effect on AMPA receptor activity. Apart from its activity on NMDA and AMPA receptors, the compound also shows inhibition of Human Jumonji Domain Containing 2E (JMJD2E) and the malarial parasite plastid, with respective potencies of 25118.9 nM and 10417.9 nM. It acts as an agonist of the mutation responsible for Fibrous Dysplasia/McCune-Albright Syndrome with a potency of 5011.9 nM and exhibits dose-dependent inhibition of TPA-induced Epstein-Barr virus early antigen activation in human Raji cells while also displaying cytotoxicity at higher concentrations. Additionally, 27688 inhibits D-amino acid oxidase in porcine kidney homogenate (IC50: 33600.0 nM) and activates Trypanosoma cruzi cruzain. It shows an inhibitory effect on Cryptosporidium hominis TS-DHFR and on HIV-1 subtype B reverse transcriptase, albeit with low inhibition percentages at higher concentrations..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	DHQ (2,3-dihydroxy-quinoxalin) is an inducer of ATPase activity that of Herpes Simplex Virus thymidine kinase.
别名	2,3-二羟基喹喔啉, 2,3-dihydroxy-quinoxalin

化学信息

分子量	162.15
分子式	C₈H₆N₂O₂
CAS No.	15804-19-0
Smiles	OC1=NC2=CC=CC=C2N=C1O
密度	1.336g/cm3

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

DMSO: 60 mg/mL (370.03 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.1671 mL	30.8356 mL	61.6713 mL	308.3565 mL
5 mM	1.2334 mL	6.1671 mL	12.3343 mL	61.6713 mL
10 mM	0.6167 mL	3.0836 mL	6.1671 mL	30.8356 mL
20 mM	0.3084 mL	1.5418 mL	3.0836 mL	15.4178 mL
50 mM	0.1233 mL	0.6167 mL	1.2334 mL	6.1671 mL
100 mM	0.0617 mL	0.3084 mL	0.6167 mL	3.0836 mL

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。