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顶部生物活性储存和溶解信息计算器

Anti-TFAP2A Antibody (2N525)

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Anti-TFAP2A Antibody (2N525)
产品编号 TMAC-04008
别名 Transcription factor AP-2-alpha, Transcription factor AP2 alpha, Transcription factor AP 2 alpha (activating enhancer binding protein 2 alpha), TFAP2A, TFAP2, TFAP 2A, TFAP 2, FLJ51761, BOFS, AP2TF, AP2-alpha, AP2A_HUMAN, AP-2 transcription factor, AP2 Transcription Factor, AP-2, AP2, AP 2alpha, AP 2 transcription factor, Activator protein 2, Activating enhancer-binding protein 2-alpha, Activating enhancer binding protein 2 alpha

Anti-TFAP2A Antibody (2N525) 是一种 Mouse 抗体，靶向 TFAP2A。Anti-TFAP2A Antibody (2N525) 可用于 WB,ICC,FCM。

Anti-TFAP2A Antibody (2N525)

Anti-TFAP2A Antibody (2N525)

Rating icon 还可以
Anti-TFAP2A Antibody (2N525)
产品编号 TMAC-04008 别名 Transcription factor AP-2-alpha, Transcription factor AP2 alpha, Transcription factor AP 2 alpha (activating enhancer binding protein 2 alpha), TFAP2A, TFAP2, TFAP 2A, TFAP 2, FLJ51761, BOFS, AP2TF, AP2-alpha, AP2A_HUMAN, AP-2 transcription factor, AP2 Transcription Factor, AP-2, AP2, AP 2alpha, AP 2 transcription factor, Activator protein 2, Activating enhancer-binding protein 2-alpha, Activating enhancer binding protein 2 alpha

Anti-TFAP2A Antibody (2N525) 是一种 Mouse 抗体，靶向 TFAP2A。Anti-TFAP2A Antibody (2N525) 可用于 WB,ICC,FCM。

规格价格库存数量
50 μL
¥ 1,995
5日内发货
100 μL
¥ 2,985
5日内发货
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产品介绍

生物活性
产品描述
Anti-TFAP2A Antibody (2N525) is a Mouse antibody targeting TFAP2A. Anti-TFAP2A Antibody (2N525) can be used in WB,ICC,FCM.
别名Transcription factor AP-2-alpha, Transcription factor AP2 alpha, Transcription factor AP 2 alpha (activating enhancer binding protein 2 alpha), TFAP2A, TFAP2, TFAP 2A, TFAP 2, FLJ51761, BOFS, AP2TF, AP2-alpha, AP2A_HUMAN, AP-2 transcription factor, AP2 Transcription Factor, AP-2, AP2, AP 2alpha, AP 2 transcription factor, Activator protein 2, Activating enhancer-binding protein 2-alpha, Activating enhancer binding protein 2 alpha
交叉反应
Human
验证活性
1. Western blot analysis of AP2 alpha on human AP2 alpha recombinant protein using anti- AP2 alpha antibody at 1/1,000 dilution.
2. Western blot analysis of AP2 alpha on HEK293 (1) and AP2 alpha -hIgGFc transfected HEK293 (2) cell lysate using anti- AP2 alpha antibody at 1/1,000 dilution.
3. ICC staining AP2 alpha (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. Flow cytometric analysis of Hela cells with AP2 alpha antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
应用
WB
ICC
FCM
推荐剂量
WB: 1:500-2000; ICC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景AP-2 transcription factor family members include AP-2α, AP-2β and AP-2γ, which specifically bind to the DNA consensus sequence CCCCAGGC and initiate transcription of selected genes. AP-2, also known as ERF-1, plays a role in regulating estrogen receptor expression. AP-2β, a splice variant of AP-2α, inhibits AP-2 activity. Besides subscribing to the AP-2 complex, AP-2α, AP-2β and AP-2γ proteins compose the OB2-1 transcription factor complex. OB2-1 specifically upregulates expression of the proto-oncogene c-ErbB-2, which is overexpressed in 25-30% of breast cancers. AP-2α may play an important role in the development of ectodermal-derived tissues. Deleterious mutations involving the AP-2α gene are linked to microphthalmia, corneal clouding and other anterior eye chamber defects. The ubiquitously expressed AP-4 transcription factor specifically binds to the DNA consensus sequence 5'-CAGCTG-3'. AP-4 interacts with promoters for immunoglobulin-κ gene families and simian virus 40. AP-4 may enhance the transcription of the human Huntington's disease gene. AP-4 is a helix-loop-helix protein that contains two distinctive leucine repeat elements.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P05549
化学信息
分子量Theoretical: 48 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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