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Anti-CASC5 Polyclonal Antibody

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货号 TMAB-03638

Anti-CASC5 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CASC5。Anti-CASC5 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-CASC5 Polyclonal Antibody

Anti-CASC5 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-03638

Anti-CASC5 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CASC5。Anti-CASC5 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-CASC5 Polyclonal Antibody is a Rabbit antibody targeting CASC5. Anti-CASC5 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Dog,Cow,Horse,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Chromosome, centromere, kinetochore.
组织特异性Highly expressed in testis, where it is localized in germ cells, in particular in spermatocytes and in the pre-acrosome of round spermatids. Detected in the acrosome of ejaculated spermatozoa. Detected in adult thymus, bone marrow, colon, small intestine, appendix and placenta, and in fetal liver and thymus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Four known isoforms exist.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CASC5
抗原种属
Human
基因名称
KNL1
基因ID
蛋白名称
Kinetochore scaffold 1
Uniprot ID
功能
Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Required for attachment of the kinetochores to the spindle microtubules. Directly links BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper chromosome segregation during mitosis. Acts in coordination with CENPK to recruit the NDC80 complex to the outer kinetochore.
化学信息
分子量Theoretical: 265 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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