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Anti-GPR109A Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GPR109A。Anti-GPR109A Polyclonal Antibody 可用于 WB。
Anti-GPR109A Polyclonal Antibody 是一种 Rabbit 抗体,靶向 GPR109A。Anti-GPR109A Polyclonal Antibody 可用于 WB。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,160 | 5日内发货 | |
100 μL | ¥ 1,965 | 5日内发货 | |
200 μL | ¥ 2,785 | 5日内发货 |
产品描述 | Anti-GPR109A Polyclonal Antibody is a Rabbit antibody targeting GPR109A. Anti-GPR109A Polyclonal Antibody can be used in WB. |
Ig Type | IgG |
交叉反应 | Human,Mouse (predicted:Rat,Cow,Rabbit) |
验证活性 | Sample: Skin (Mouse) Lysate at 40 μg Primary: Anti-GPR109R (TMAB-00787) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kDa Observed band size: 40 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis. |
免疫原 | KLH conjugated synthetic peptide: human GPR109A/HM74A |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Hydrolysis,p53 Pathway,Hydrolysis,Cancer,GPCR |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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