购物车
- 全部删除
您的购物车当前为空
Anti-GPR109A Polyclonal Antibody
还可以
产品编号 TMAB-00787
别名 rHM74b, Puma-g, PUMAG, Pumag, Puma g, Protein PUMA-G, Nicotinic acid receptor 1, Nicotinic acid receptor, NIACR1, Niacr1, Niacin receptor 1, Interferon gamma inducible gene Puma g, HM74b, HM74a, HM74A, HCAR2, G-protein coupled receptor HM74, G-protein coupled receptor 109A, G-protein coupled receptor 109, GPR109A, G protein coupled receptor Hm74b, G protein coupled receptor HM74a
Anti-GPR109A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GPR109A。Anti-GPR109A Polyclonal Antibody 可用于 WB。
Anti-GPR109A Polyclonal Antibody
Anti-GPR109A Polyclonal Antibody
还可以产品编号 TMAB-00787 别名 rHM74b, Puma-g, PUMAG, Pumag, Puma g, Protein PUMA-G, Nicotinic acid receptor 1, Nicotinic acid receptor, NIACR1, Niacr1, Niacin receptor 1, Interferon gamma inducible gene Puma g, HM74b, HM74a, HM74A, HCAR2, G-protein coupled receptor HM74, G-protein coupled receptor 109A, G-protein coupled receptor 109, GPR109A, G protein coupled receptor Hm74b, G protein coupled receptor HM74a
Anti-GPR109A Polyclonal Antibody 是一种 Rabbit 抗体，靶向 GPR109A。Anti-GPR109A Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,160 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
大包装 & 定制
加入购物车
TargetMol 的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
联系我们获取更多批次信息
资源下载
产品介绍
生物活性
抗原信息
化学信息
| 产品描述 | Anti-GPR109A Polyclonal Antibody is a Rabbit antibody targeting GPR109A. Anti-GPR109A Polyclonal Antibody can be used in WB. |
| 别名 | rHM74b, Puma-g, PUMAG, Pumag, Puma g, Protein PUMA-G, Nicotinic acid receptor 1, Nicotinic acid receptor, NIACR1, Niacr1, Niacin receptor 1, Interferon gamma inducible gene Puma g, HM74b, HM74a, HM74A, HCAR2, G-protein coupled receptor HM74, G-protein coupled receptor 109A, G-protein coupled receptor 109, GPR109A, G protein coupled receptor Hm74b, G protein coupled receptor HM74a |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse (predicted:Rat,Cow,Rabbit) |
| 验证活性 | Sample: Skin (Mouse) Lysate at 40 μg Primary: Anti-GPR109R (TMAB-00787) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 40 kDa Observed band size: 40 kDa |
| 应用 | |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. |
| 组织特异性 | Expression largely restricted to adipose tissue and spleen. Expressed on mature neutrophils but not on immature neutrophils or eosinophils. |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis. |
| 免疫原 | KLH conjugated synthetic peptide: human GPR109A/HM74A |
| 抗原种属 | Human |
| 基因名称 | HCAR2 |
| 基因ID | |
| 蛋白名称 | Hydroxycarboxylic acid receptor 2 |
| Uniprot ID | |
| 研究领域 | Hydrolysis,p53 Pathway,Hydrolysis,Cancer,GPCR |
| 功能 | Acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins, leading to neutrophil apoptosis. The rank order of potency for the displacement of nicotinic acid binding is 5-methyl pyrazole-3-carboxylic acid = pyridine-3-acetic acid > acifran > 5-methyl nicotinic acid = acipimox >> nicotinuric acid = nicotinamide. |
| 分子量 | Theoretical: 40 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
SCI 文献
评论列表
预览
Related Tags: buy Anti-GPR109A Polyclonal Antibody | purchase Anti-GPR109A Polyclonal Antibody | Anti-GPR109A Polyclonal Antibody cost | order Anti-GPR109A Polyclonal Antibody | Anti-GPR109A Polyclonal Antibody molecular weight
嗨！有任何问题？点我咨询
评论内容