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Anti-MAP2K1IP1 Polyclonal Antibody

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货号 TMAB-08565

Anti-MAP2K1IP1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MAP2K1IP1。Anti-MAP2K1IP1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-MAP2K1IP1 Polyclonal Antibody

Anti-MAP2K1IP1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-08565

Anti-MAP2K1IP1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MAP2K1IP1。Anti-MAP2K1IP1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-MAP2K1IP1 Polyclonal Antibody is a Rabbit antibody targeting MAP2K1IP1. Anti-MAP2K1IP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Chicken,Cow,Zebrafish)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Late endosome membrane.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011]
抗原信息
免疫原
KLH conjugated synthetic peptide: human MAP2K1IP1
抗原种属
Human
基因名称
LAMTOR3
基因ID
蛋白名称
Ragulator complex protein LAMTOR3
Uniprot ID
功能
As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.
化学信息
分子量Theoretical: 13.6 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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