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别名 snRNA (2'-O-methyladenosine-N(6)-)-methyltransferase METTL4, N(6)-adenine-specific methyltransferase METTL4, N(6)-adenine-specific DNA methyltransferase METTL4, METTL4, Methyltransferase-like protein 4
Anti-METTL4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 METTL4。Anti-METTL4 Polyclonal Antibody 可用于 WB。
Anti-METTL4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 METTL4。Anti-METTL4 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-METTL4 Polyclonal Antibody is a Rabbit antibody targeting METTL4. Anti-METTL4 Polyclonal Antibody can be used in WB. |
| 别名 | snRNA (2'-O-methyladenosine-N(6)-)-methyltransferase METTL4, N(6)-adenine-specific methyltransferase METTL4, N(6)-adenine-specific DNA methyltransferase METTL4, METTL4, Methyltransferase-like protein 4 |
| Ig Type | IgG |
| 反应种属 | Mouse,Rat (predicted:Human,Dog,Horse,Rabbit) |
| 验证活性 | 1. Sample: Liver (Rat) Cell Lysate at 40 μg Primary: Anti-METTL4 (TMAB-01128) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kDa Observed band size: 54 kDa 2. Sample: Lane 1: Mouse Heart tissue lysates Lane 2: Rat Cerebrum tissue lysates Primary: Anti-METTL4 (TMAB-01128) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 54 kDa Observed band size: 54 kDa ![]() ![]() |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1 mg/mL |
| 研究背景 | METTL4 is a 472 amino acid enzyme that belongs to the MT-A70-like family. Other members of this family have enzymatic activity that results in the transfer of a methyl group to and from DNA, RNA or amino acids. The gene encoding METTL4 maps to chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases, representing about 2.5% of total DNA in cells. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. Also, three chromosomal abnormalities result from meiotic nondisjunction events of chromosome 18: Monosomy 18p, Trisomy 18 (also known as Edwards syndrome) and Tetrasomy 18p. |
| 免疫原 | KLH conjugated synthetic peptide: human METTL4 |
| 抗原种属 | Human |
| 基因名称 | METTL4 |
| 基因ID | |
| 蛋白名称 | N(6)-adenine-specific methyltransferase METTL4 |
| Uniprot ID | |
| 研究领域 | Methylated DNA,DNMTs,Methylated DNA Associated,Other Nuclear Bodies |
| 功能 | Probable methyltransferase. |
| 分子量 | Theoretical: 54 kDa. |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | store at -20°C |