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Anti-CD93/C1qR1 Antibody (8N985)
还可以产品编号 TMAY-02387
Anti-CD93/C1qR1 Antibody (8N985) 是一种 Mouse 抗体，靶向 CD93/C1qR1。Anti-CD93/C1qR1 Antibody (8N985) 可用于 FCM。
Anti-CD93/C1qR1 Antibody (8N985)
Anti-CD93/C1qR1 Antibody (8N985)
还可以产品编号 TMAY-02387
Anti-CD93/C1qR1 Antibody (8N985) 是一种 Mouse 抗体，靶向 CD93/C1qR1。Anti-CD93/C1qR1 Antibody (8N985) 可用于 FCM。
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偶联与修饰
抗原信息
| 产品描述 | Anti-CD93/C1qR1 Antibody (8N985) is a Mouse antibody targeting CD93/C1qR1. Anti-CD93/C1qR1 Antibody (8N985) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG2a |
| 克隆号 | 8N985 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human CD93 expression on human whole blood monocytes. Cells were stained with purified anti-Human CD93, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
| 应用 | FCM |
| 推荐剂量 | FCM: 1:25-1:100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD93 / C1qR (rh CD93 / C1qR; TMPY-02268; Q9NPY3; Met1-Lys580). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes, neutrophils, endothelial cells, and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR, a receptor expressed during early B-cell development, is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive, memory, and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches. |
| 偶联 | Unconjugated |
| 其他可选修饰符 | APC/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human CD93 / C1qR Protein (TMPY-02268) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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