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顶部生物活性储存和溶解信息计算器

Anti-CD93/C1qR1 Antibody (8N985)

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产品编号 TMAY-02387
别名 Ly68, CD93 molecule, C1qrp, C1qr1, AW555904, AA4.1, AA145088, 6030404G09Rik

Anti-CD93/C1qR1 Antibody (8N985) 是一种 Mouse 抗体，靶向 CD93/C1qR1。Anti-CD93/C1qR1 Antibody (8N985) 可用于 FCM。

Anti-CD93/C1qR1 Antibody (8N985)

Anti-CD93/C1qR1 Antibody (8N985)

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Rating icon 还可以
产品编号 TMAY-02387 别名 Ly68, CD93 molecule, C1qrp, C1qr1, AW555904, AA4.1, AA145088, 6030404G09Rik

Anti-CD93/C1qR1 Antibody (8N985) 是一种 Mouse 抗体，靶向 CD93/C1qR1。Anti-CD93/C1qR1 Antibody (8N985) 可用于 FCM。

规格价格库存数量
100 μL
¥ 1,679
5日内发货
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产品介绍

生物活性
产品描述
Anti-CD93/C1qR1 Antibody (8N985) is a Mouse antibody targeting CD93/C1qR1. Anti-CD93/C1qR1 Antibody (8N985) can be used in FCM.
别名Ly68, CD93 molecule, C1qrp, C1qr1, AW555904, AA4.1, AA145088, 6030404G09Rik
Ig Type
Mouse IgG2a
克隆号
8N985
交叉反应
Human
特异性
Human C1qR1/CD93
验证活性
Flow cytometric analysis of Human CD93 expression on human whole blood monocytes. Cells were stained with purified anti-Human CD93, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes.
应用FCM
推荐剂量
FCM: 1:25-1:100
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD93 / C1qR (rh CD93 / C1qR; TMPY-02268; Q9NPY3; Met1-Lys580). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes, neutrophils, endothelial cells, and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR, a receptor expressed during early B-cell development, is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive, memory, and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
APC/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Human CD93 / C1qR Protein (TMPY-02268)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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关键词

AW-555904AW 555904AA-145088AA 145088

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